[HTML][HTML] The Functioning of Na+-ATPases from Protozoan Parasites: Are These Pumps Targets for Antiparasitic Drugs?

CF Dick, JR Meyer-Fernandes, A Vieyra�- Cells, 2020 - mdpi.com
The ENA ATPases (from exitus natru: the exit of sodium) belonging to the P-type ATPases
are structurally very similar to the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA); they�…

Opportunistic free-living amoebal pathogens

MR Mungroo, NA Khan, S Maciver…�- Pathogens and Global�…, 2022 - Taylor & Francis
Pathogenic free-living amoebae affecting the central nervous system are known to cause
granulomatous amoebic encephalitis (GAE) or primary amoebic meningoencephalitis�…

[HTML][HTML] On the origin of the functional versatility of macrophages

A Bajgar, G Krejčov�- Frontiers in Physiology, 2023 - frontiersin.org
Macrophages represent the most functionally versatile cells in the animal body. In addition to
recognizing and destroying pathogens, macrophages remove senescent and exhausted�…

Potential anti-amoebic activity of sulfonate-and sulfamate-containing carboxamide derivatives against pathogenic Acanthamoeba castellanii belonging to the�…

N Akbar, R Siddiqui, MI El-Gamal, SO Zaraei…�- Parasitology�…, 2024 - Elsevier
Acanthamoeba are ubiquitously distributed in the environment and can cause infection of
the central nervous system as well a sight-threatening eye infection. Herein, the potential�…

Novel anti-Acanthamoebic properties of raloxifene sulfonate/sulfamate derivatives

R Siddiqui, MI El-Gamal, S Sajeev, SO Zaraei…�- Molecular and�…, 2023 - Elsevier
Acanthamoeba are known to cause a vision threatening eye infection typically due to contact
lens wear, and an infection of the central nervous system. The ability of these amoebae to�…

Antiamoebic properties of methyltrioctylammonium chloride based deep eutectic solvents

R Siddiqui, Z Makhlouf, N Akbar, M Khamis…�- Contact Lens and�…, 2023 - Elsevier
Purpose This aim of this study was to assess anti-parasitic properties of deep eutectic
solvents against eye pathogen, Acanthamoeba, often associated with the use of contact�…

Acanthamoeba spp. monoclonal antibody against a CPA2 transporter: a promising molecular tool for acanthamoebiasis diagnosis and encystment study

MM Weber-Lima, B Prado-Costa, A Becker-Finco…�- Parasitology, 2020 - cambridge.org
Free-living amoeba of the genus Acanthamoeba are ubiquitous protozoa involved in
opportunistic and non-opportunistic infection in humans, such as granulomatous amoebic�…

[HTML][HTML] Enhancement of capsular hypermucoviscosity in Klebsiella pneumoniae by Acanthamoeba

JM Huang, KC Sung, WC Lin, HY Lai…�- PLoS neglected tropical�…, 2023 - journals.plos.org
Background Acanthamoeba and Klebsiella pneumoniae are both environmental
commensals. Recently, clinical harm caused by hypermucoviscous K. pneumoniae has�…

[HTML][HTML] Ouabain, ATPase inhibitor, potentially enhances the effect of polyhexamethylene biguanide on Acanthamoeba castellanii

KY Shih, YT Chang, YJ Wang, JM Huang�- International Journal for�…, 2024 - Elsevier
Acanthamoeba, a free-living amoeba, is commonly found in various natural environments,
such as rivers and soil, as well as in public baths, swimming pools, and sewers�…

Current strategies to treat Acanthamoeba keratitis: a patent overview

R Siddiqui, NA Khan�- Pharmaceutical patent analyst, 2020 - Taylor & Francis
In countries such as the UK, approximately one in 10,000 contact lens wearers experience
Acanthamoeba keratitis (AK). This is a significant number considering the number of contact�…