[HTML][HTML] Next-generation sequencing: insights to advance clinical investigations of the microbiome
CR Wensel, JL Pluznick, SL Salzberg…�- The Journal of clinical�…, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable�…
human microbiome by allowing for the discovery and characterization of unculturable�…
Best practices for analysing microbiomes
Complex microbial communities shape the dynamics of various environments, ranging from
the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies�…
the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies�…
[HTML][HTML] Microbiome definition re-visited: old concepts and new challenges
The field of microbiome research has evolved rapidly over the past few decades and has
become a topic of great scientific and public interest. As a result of this rapid growth in�…
become a topic of great scientific and public interest. As a result of this rapid growth in�…
[HTML][HTML] Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis
The 16S rRNA gene has been a mainstay of sequence-based bacterial analysis for
decades. However, high-throughput sequencing of the full gene has only recently become a�…
decades. However, high-throughput sequencing of the full gene has only recently become a�…
Using MicrobiomeAnalyst for comprehensive statistical, functional, and meta-analysis of microbiome data
MicrobiomeAnalyst is an easy-to-use, web-based platform for comprehensive analysis of
common data outputs generated from current microbiome studies. It enables researchers�…
common data outputs generated from current microbiome studies. It enables researchers�…
MicrobiomeAnalyst 2.0: comprehensive statistical, functional and integrative analysis of microbiome data
Microbiome studies have become routine in biomedical, agricultural and environmental
sciences with diverse aims, including diversity profiling, functional characterization, and�…
sciences with diverse aims, including diversity profiling, functional characterization, and�…
[HTML][HTML] Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics data
Background The accuracy of microbial community surveys based on marker-gene and
metagenomic sequencing (MGS) suffers from the presence of contaminants—DNA�…
metagenomic sequencing (MGS) suffers from the presence of contaminants—DNA�…
[HTML][HTML] A communal catalogue reveals Earth's multiscale microbial diversity
LR Thompson, JG Sanders, D McDonald, A Amir…�- Nature, 2017 - nature.com
Our growing awareness of the microbial world's importance and diversity contrasts starkly
with our limited understanding of its fundamental structure. Despite recent advances in DNA�…
with our limited understanding of its fundamental structure. Despite recent advances in DNA�…
[HTML][HTML] Comparison between 16S rRNA and shotgun sequencing data for the taxonomic characterization of the gut microbiota
In this paper we compared taxonomic results obtained by metataxonomics (16S rRNA gene
sequencing) and metagenomics (whole shotgun metagenomic sequencing) to investigate�…
sequencing) and metagenomics (whole shotgun metagenomic sequencing) to investigate�…
[HTML][HTML] Developmental trajectory of the healthy human gut microbiota during the first 5 years of life
J Roswall, LM Olsson, P Kovatcheva-Datchary…�- Cell host &�…, 2021 - cell.com
The gut is inhabited by a densely populated ecosystem, the gut microbiota, that is
established at birth. However, the succession by which different bacteria are incorporated�…
established at birth. However, the succession by which different bacteria are incorporated�…