The biology and functional importance of MAIT cells
DI Godfrey, HF Koay, J McCluskey, NA Gherardin�- Nature immunology, 2019 - nature.com
In recent years, a population of unconventional T cells called 'mucosal-associated invariant
T cells'(MAIT cells) has captured the attention of immunologists and clinicians due to their�…
T cells'(MAIT cells) has captured the attention of immunologists and clinicians due to their�…
Control of immunity by the microbiota
The immune system has coevolved with extensive microbial communities living on barrier
sites that are collectively known as the microbiota. It is increasingly clear that microbial�…
sites that are collectively known as the microbiota. It is increasingly clear that microbial�…
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch…�- European journal of�…, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical�…
immunology and flow cytometry community. They provide the theory and key practical�…
MAIT cells are imprinted by the microbiota in early life and promote tissue repair
MG Constantinides, VM Link, S Tamoutounour…�- Science, 2019 - science.org
INTRODUCTION The microbiota promotes the maturation and homeostasis of the immune
system, in part through the release of microbial products. Early-life microbial colonization�…
system, in part through the release of microbial products. Early-life microbial colonization�…
[HTML][HTML] B vitamins and their role in immune regulation and cancer
B group vitamins represent essential micronutrients for myriad metabolic and regulatory
processes required for human health, serving as cofactors used by hundreds of enzymes�…
processes required for human health, serving as cofactors used by hundreds of enzymes�…
Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge
DG Pellicci, HF Koay, SP Berzins�- Nature Reviews Immunology, 2020 - nature.com
T cell lineages are defined by specialized functions and differential expression of surface
antigens, cytokines and transcription factors. Conventional CD4+ and CD8+ T cells are the�…
antigens, cytokines and transcription factors. Conventional CD4+ and CD8+ T cells are the�…
Mucosal-associated invariant T cells and disease
A Toubal, I Nel, S Lotersztajn, A Lehuen�- Nature Reviews Immunology, 2019 - nature.com
Mucosal-associated invariant T (MAIT) cells are unique innate-like T cells that bridge innate
and adaptive immunity. They are activated by conserved bacterial ligands derived from�…
and adaptive immunity. They are activated by conserved bacterial ligands derived from�…
[HTML][HTML] Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that recognize microbial
metabolites through a semi-invariant T cell receptor (TCR). Major questions remain�…
metabolites through a semi-invariant T cell receptor (TCR). Major questions remain�…
Microbial metabolites control the thymic development of mucosal-associated invariant T cells
F Legoux, D Bellet, C Daviaud, Y El Morr, A Darbois…�- Science, 2019 - science.org
How the microbiota modulate immune functions remains poorly understood. Mucosal-
associated invariant T (MAIT) cells are implicated in mucosal homeostasis and absent in�…
associated invariant T (MAIT) cells are implicated in mucosal homeostasis and absent in�…
Early-life imprinting of unconventional T cells and tissue homeostasis
MG Constantinides, Y Belkaid�- Science, 2021 - science.org
BACKGROUND In addition to providing antimicrobial immunity, the immune system governs
numerous aspects of host physiology, in part through the coordinated action of tissue�…
numerous aspects of host physiology, in part through the coordinated action of tissue�…