Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By�…

The immune system employs recognition tools to communicate with its microbial
evolutionary partner. Among all the methods of microbial perception, T cells enable the�…

Summary Gut interleukin-17A (IL-17)-producing γδ T cells are tissue-resident cells that are
involved in both host defense and regulation of intestinal inflammation. However, factors that�…

Human milk oligosaccharides: potential therapeutic aids for allergic diseases: Trends in
Immunology Skip to Main Content Advertisement Trends in Immunology This journal offers�…

Early-life cues shape the immune system during adulthood. However, early-life signaling
pathways and their temporal functions are not well understood. Herein, we demonstrate that�…

Clostridioides difficile is often resistant to the actions of antibiotics to treat other bacterial
infections and the resulting C. difficile infection (CDI) is among the leading causes of�…

Clostridioides difficile infection (CDI) represents a significant challenge to public health. C.
difficile-associated mortality and morbidity have led the US CDC to designate it as an urgent�…

Pathobionts are opportunistic microbes that emerge as a result of perturbations in the
healthy microbiome due to complex interactions of various genetic, exposomal, microbial�…

The immune-pathology in Crohn's disease is linked to dysregulated CD4+ T cell responses
biased towards pathogenic TH17 cells. However, the role of CD8+ T cells able to produce IL�…

While γδ T cells are present virtually in all vertebrates, there is a remarkable lack of
conservation of the TRG and TRD loci underlying the generation of the γδ T cell receptor�…