Epidemiology and aetiology of heart failure

B Ziaeian, GC Fonarow�- Nature Reviews Cardiology, 2016 - nature.com
Heart failure (HF) is a rapidly growing public health issue with an estimated prevalence of>
37.7 million individuals globally. HF is a shared chronic phase of cardiac functional�…

Do no harm: a roadmap for responsible machine learning for health care

J Wiens, S Saria, M Sendak, M Ghassemi, VX Liu…�- Nature medicine, 2019 - nature.com
Interest in machine-learning applications within medicine has been growing, but few studies
have progressed to deployment in patient care. We present a framework, context and�…

[HTML][HTML] Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational�…

T Gilbert, J Neuburger, J Kraindler, E Keeble, P Smith…�- The Lancet, 2018 - thelancet.com
Background Older people are increasing users of health care globally. We aimed to
establish whether older people with characteristics of frailty and who are at risk of adverse�…

Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis

AY Walley, Z Xuan, HH Hackman, E Quinn…�- Bmj, 2013 - bmj.com
Objective To evaluate the impact of state supported overdose education and nasal naloxone
distribution (OEND) programs on rates of opioid related death from overdose and acute care�…

Eradication of hepatitis C virus infection in patients with cirrhosis reduces risk of liver and non-liver complications

P Nahon, V Bourcier, R Layese, E Audureau, C Cagnot…�- Gastroenterology, 2017 - Elsevier
Background & Aims We performed a prospective study to investigate the effects of a
sustained viral response (SVR) on outcomes of patients with hepatitis C virus (HCV)�…

Validation of the National Health Insurance Research Database with ischemic stroke cases in Taiwan

CL Cheng, YHY Kao, SJ Lin, CH Lee…�- …�and drug safety, 2011 - Wiley Online Library
Abstract Objective The National Health Insurance Research Database (NHIRD) is commonly
used for pharmacoepidemiological research in Taiwan. This study evaluated the validity of�…

Using phecodes for research with the electronic health record: from PheWAS to PheRS

L Bastarache�- Annual review of biomedical data science, 2021 - annualreviews.org
Electronic health records (EHRs) are a rich source of data for researchers, but extracting
meaningful information out of this highly complex data source is challenging. Phecodes�…

[HTML][HTML] A review of challenges and opportunities in machine learning for health

M Ghassemi, T Naumann, P Schulam…�- AMIA Summits on�…, 2020 - ncbi.nlm.nih.gov
Modern electronic health records (EHRs) provide data to answer clinically meaningful
questions. The growing data in EHRs makes healthcare ripe for the use of machine learning�…

Caveats for the use of operational electronic health record data in comparative effectiveness research

WR Hersh, MG Weiner, PJ Embi, JR Logan…�- Medical care, 2013 - journals.lww.com
The growing amount of data in operational electronic health record systems provides
unprecedented opportunity for its reuse for many tasks, including comparative effectiveness�…

[HTML][HTML] Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record

WQ Wei, LA Bastarache, RJ Carroll, JE Marlo…�- PloS one, 2017 - journals.plos.org
Objective To compare three groupings of Electronic Health Record (EHR) billing codes for
their ability to represent clinically meaningful phenotypes and to replicate known genetic�…