Abstract PI3K/AKT signaling leads to reduced apoptosis, stimulates cell growth and
increases proliferation. Under normal conditions, PI3K/AKT activation is tightly controlled�…

CK2 genes are overexpressed in many human cancers, and most often overexpression is
associated with worse prognosis. Site-specific expression in mice leads to cancer�…

N6-methyladenosine (m6A) is the most commonly occurring internal RNA modification to be
found in eukaryotic mRNA and serves an important role in various physiological events�…

Achieving sufficient coverage of regulatory phosphorylation sites by mass spectrometry (MS)-
based phosphoproteomics for signaling pathway reconstitution is challenging, especially�…

Cancer is a leading cause of death worldwide. Cancer cells proliferate uncontrollably and,
many cases, spread to other parts of the body. A protein historically involved in cancer is�…

Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study,
bioinformatics analyses were conducted to identify possible pathogenic roles of CK2α�…

The association of protein kinase CK2 (formerly casein kinase II or 2) with cell growth and
proliferation in cells was apparent at early stages of its investigation. A cancer-specific role�…

Abstract Background and Objectives To investigate the expression dynamics of CD73 and
its prognostic significance in human colorectal cancer (CRC). Methods CD73 expression�…

MicroRNAs (miRNAs) play important roles in diverse biological processes and are emerging
as key regulators of tumorigenesis and tumor progression. To explore the dysregulation of�…

Protein kinase CK2 (CK2) is a ubiquitous holoenzyme involved in a wide array of
developmental processes. The involvement of CK2 in events such as neurogenesis�…