A balancing act: The role of pro‐and anti‐stress peptides within the central amygdala in anxiety and alcohol use disorders
LC Walker�- Journal of neurochemistry, 2021 - Wiley Online Library
The central nucleus of the amygdala (CeA) is widely implicated as a structure that integrates
both appetitive and aversive stimuli. While intrinsic CeA microcircuits primarily consist of�…
both appetitive and aversive stimuli. While intrinsic CeA microcircuits primarily consist of�…
[HTML][HTML] Expression and distribution of neuropeptide-expressing cells throughout the rodent paraventricular nucleus of the thalamus
The paraventricular nucleus of the thalamus (PVT) has been shown to make significant
contributions to affective and motivated behavior, but a comprehensive description of the�…
contributions to affective and motivated behavior, but a comprehensive description of the�…
Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis
Aims To determine the underlying cellular changes and clinical correlates associated with
pathology of the hypothalamus in amyotrophic lateral sclerosis (ALS), as hypothalamic�…
pathology of the hypothalamus in amyotrophic lateral sclerosis (ALS), as hypothalamic�…
Peptidomic analysis reveals seasonal neuropeptide and peptide hormone changes in the hypothalamus and pituitary of a hibernating mammal
During the winter, hibernating mammals undergo extreme changes in physiology, which
allow them to survive several months without access to food. These animals enter a state of�…
allow them to survive several months without access to food. These animals enter a state of�…
[HTML][HTML] Cocaine and amphetamine regulated transcript (CART) mediates sex differences in binge drinking through central taste circuits
XJ Maddern, B Letherby, SS Ch'ng, A Pearl…�- …, 2024 - nature.com
The neuropeptide cocaine-and amphetamine-regulated transcript (CART) has been
implicated in alcohol consumption and reward behaviours, yet mechanisms mediating these�…
implicated in alcohol consumption and reward behaviours, yet mechanisms mediating these�…
[HTML][HTML] Functionally active TRPA1 ion channel is downregulated in peptidergic neurons of the Edinger-Westphal nucleus upon acute alcohol exposure
Introduction: The centrally projecting Edinger-Westphal nucleus (EWcp) contributes to the
control of alcohol consumption by its urocortin 1 (UCN1) and cocaine-and amphetamine�…
control of alcohol consumption by its urocortin 1 (UCN1) and cocaine-and amphetamine�…
Cocaine and amphetamine regulated transcript (CART) signalling in the central nucleus of the amygdala modulates stress-induced alcohol seeking
LC Walker, LJ Hand, B Letherby, KL Huckstep…�- …, 2021 - nature.com
The central nucleus of the amygdala (CeA) is a key hub of the neural circuitry regulating
alcohol and stress interactions. However, the exact neuronal populations that govern this�…
alcohol and stress interactions. However, the exact neuronal populations that govern this�…
Orphan peptide and G protein‐coupled receptor signalling in alcohol use disorder
Neuropeptides and G protein‐coupled receptors (GPCRs) have long been, and continue to
be, one of the most popular target classes for drug discovery in CNS disorders, including�…
be, one of the most popular target classes for drug discovery in CNS disorders, including�…
Neuropeptide CART modulates dopamine turnover in the nucleus accumbens: Insights into the anatomy of rewarding circuits
SN Awathale, AG Choudhary…�- Journal of�…, 2021 - Wiley Online Library
Neuropeptide cocaine‐and amphetamine‐regulated transcript (CART) is known to influence
the activity of the canonical mesolimbic dopaminergic pathway and modulate reward�…
the activity of the canonical mesolimbic dopaminergic pathway and modulate reward�…
[HTML][HTML] Glycogen Synthase Kinase 3β Is a Key Regulator in the Inhibitory Effects of Accumbal Cocaine-and Amphetamine-Regulated Transcript Peptide 55–102 on�…
BR Cho, WY Kim, JK Jang, JW Lee, JH Kim�- International Journal of�…, 2022 - mdpi.com
Microinjection of cocaine-and amphetamine-regulated transcript (CART) peptide 55–102
into the nucleus accumbens (NAcc) core significantly attenuates psychostimulant-induced�…
into the nucleus accumbens (NAcc) core significantly attenuates psychostimulant-induced�…