Although there is consensus on the management of patients with Brugada Syndrome with
high risk for sudden cardiac arrest, asymptomatic or intermediate-risk patients present�…

Chronic cocaine exposure induces enduring neuroadaptations that facilitate motivated drug
taking. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are known to�…

Reliable, feasible analytical methods are needed for forensic and anti-doping testing of
cocaine and its most important metabolites, benzoylecgonine, ecgonine methyl ester, and�…

Cardiovascular complications from drugs of abuse are becoming more apparent because of
increased usage worldwide. Substance abuse can cause acute and chronic cardiovascular�…

Cocaine is one of the oldest and most widely used illicit drugs in the world and is
responsible for major worldwide medical and social problems. Drug addiction is a disease�…

Long-term cocaine use, as well as acute cocaine use, is associated with adverse
cardiovascular consequences, including arrhythmias, angina, myocardial infarction, heart�…

Background Substance use and cardiovascular (CV) events are increasing among pregnant
women in the United States, but association between substance use in pregnancy and CV�…

Background The use of sympathomimetic and psychoactive stimulant substances has been
described for hundreds of years. Although the use of cocaine, derived from the Erythroxylon�…

Cocaine consumption has increased over the last decade. The potent sympathomimetic
effects of the drug can lead to serious neurovascular complications in the form of ischemic�…

Background Healthy behaviors, that is, engaging in regular physical activities, maintaining a
healthy diet, limiting alcohol consumption, and avoiding tobacco and drug use, decrease the�…