[HTML][HTML] The role of glp-1 receptor agonists in insulin resistance with concomitant obesity treatment in polycystic ovary syndrome

K Bednarz, K Kowalczyk, M Cwynar, D Czapla…�- International journal of�…, 2022 - mdpi.com
Insulin resistance is documented in clamp studies in 75% of women with polycystic ovary
syndrome (PCOS). Although it is not included in the diagnostic criteria of PCOS, there is a�…

[HTML][HTML] Premature ovarian insufficiency: a review on the role of oxidative stress and the application of antioxidants

YQ Shi, XT Zhu, SN Zhang, YF Ma, YH Han…�- Frontiers in�…, 2023 - frontiersin.org
Normal levels of reactive oxygen species (ROS) play an important role in regulating follicular
growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance�…

[HTML][HTML] Modulation of the inflammatory response in polycystic ovary syndrome (PCOS)—searching for epigenetic factors

D Szukiewicz, S Trojanowski, A Kociszewska…�- International journal of�…, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age. Despite its incidence, the syndrome is poorly understood and remains�…

[HTML][HTML] Oxidative stress and mitochondrial dysfunction of granulosa cells in polycystic ovarian syndrome

Y Gao, Y Zou, G Wu, L Zheng�- Frontiers in Medicine, 2023 - frontiersin.org
Polycystic ovarian syndrome (PCOS) is one of the leading causes of anovulatory infertility in
women, affecting 5%–15% of women of reproductive age worldwide. The clinical�…

Serum granulosa cell-derived TNF-α promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-κB signaling

H Ye, Y Song, W Ye, C Xiong, J Li, J Miao…�- Acta Pharmacologica�…, 2023 - nature.com
Polycystic ovary syndrome (PCOS) is a disorder with endocrinal and metabolic problems in
reproductive aged women. Evidence shows that PCOS is in a high prone trend to develop�…

Novel insights into the synergistic effects of selenium nanoparticles and metformin treatment of letrozole-induced polycystic ovarian syndrome: targeting PI3K/Akt�…

HM Rabah, DA Mohamed, RA Mariah…�- Redox�…, 2023 - Taylor & Francis
Purpose Polycystic ovary syndrome (PCOS) has a series of reproductive and metabolic
consequences. Although the link between PCOS, IR, and obesity, their impact on the�…

[HTML][HTML] A review of nitric oxide and oxidative stress in typical ovulatory women and in the pathogenesis of ovulatory dysfunction in PCOS

AO Awonuga, OG Camp, HM Abu-Soud�- Reproductive Biology and�…, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a heterogeneous functional endocrine disorder
associated with a low-grade, chronic inflammatory state. Patients with PCOS present an�…

Concurrent Diagnosis of Renal Calculi, Uterine Fibroids and Ovarian Cysts: A Complex Case Study

SS Lakshmi, PNK Sarella, K Adarsh, PL Padmini…�- Journal of Clinical and�…, 2023 - jcpr.in
This case report presents a complex clinical scenario in a 41-year-old female patient,
highlighting the concurrent diagnosis of renal calculi, uterine fibroids, and ovarian cysts. The�…

The role and participation of immune cells in the endometrial tumor microenvironment

DK Dey, D Krause, R Rai, S Choudhary…�- Pharmacology &�…, 2023 - Elsevier
The tumor microenvironment is surrounded by blood vessels and consists of malignant,
nonmalignant, and immune cells, as well as signalling molecules, which primarily affect the�…

[HTML][HTML] E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut�…

M Luo, Y Chen, X Pan, H Chen, L Fan…�- Frontiers in�…, 2023 - frontiersin.org
Objective Gut microbiota and its metabolites have regulatory effects on PCOS related
ovarian dysfunction and insulin resistance. Escherichia coli Nissle 1917 (EcN) is a�…