Numerous animal and human studies have assessed the relationship between polyphenols
and outcomes related to depression. However, no comprehensive synthesis of the main�…

Depression is a neuropsychiatric disorder associated with persistent stress and disruption of
neuronal function. Persistent stress causes neuronal atrophy, including loss of synapses�…

Background Owing to the early suffering age and the rising incidence of type 1 diabetes
(T1D), the resulting male reproductive dysfunction and fertility decline have become a�…

A novel functional food for hyperlipidemia named icariin (ICA) pro-glycymicelles (ICA-PGs)
using glycyrrhizin as a phytonanomaterial was easily prepared with improved storage, pH�…

Recent evidence suggests that diet modifies key biological factors associated with the
development of depression. It has been suggested that this could be due to the high�…

Bronchial asthma is a common chronic airway disease, and long-term management of
asthma is the focus and challenge of clinical treatment. Glucocorticoids are often used as the�…

Excessive alcohol consumption has long been identified as a risk factor for adverse atrial
remodeling and atrial fibrillation (AF). Icariin is a principal active component from traditional�…

Traditional Chinese medicine (TCM) has been practiced in the treatment of bone diseases
and alcoholism. Chronic excessive alcohol use results in alcohol-induced bone diseases�…

Significance: Currently, a large amount of evidence of beneficial effects of diets enriched
with polyphenols on various aspects of health has been accumulated. These�…

Introduction Comorbidity of bipolar disorder (BD) and alcohol use disorder (AUD) is very
frequent resulting in detrimental outcomes, including increased mortality. Diagnosis of AUD�…