[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19

B Hu, H Guo, P Zhou, ZL Shi�- Nature reviews microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute�…

Aging in COVID-19: Vulnerability, immunity and intervention

Y Chen, SL Klein, BT Garibaldi, H Li, C Wu…�- Ageing research�…, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented�…

Autopsy findings and venous thromboembolism in patients with COVID-19: a prospective cohort study

D Wichmann, JP Sperhake…�- Annals of internal�…, 2020 - acpjournals.org
Background: The new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), has caused more than 210 000 deaths worldwide. However, little is known about�…

[HTML][HTML] Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology

L Piccoli, YJ Park, MA Tortorici, N Czudnochowski…�- Cell, 2020 - cell.com
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-
CoV-2 infection is crucial for understanding immune protection and identifying targets for�…

COVID-19 Vaccine: A comprehensive status report

SP Kaur, V Gupta�- Virus research, 2020 - Elsevier
The current COVID-19 pandemic has urged the scientific community internationally to find
answers in terms of therapeutics and vaccines to control SARS-CoV-2. Published�…

[HTML][HTML] A dynamic COVID-19 immune signature includes associations with poor prognosis

AG Laing, A Lorenc, I Del Molino Del Barrio, A Das…�- Nature medicine, 2020 - nature.com
Improved understanding and management of COVID-19, a potentially life-threatening
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward�…

[HTML][HTML] Antibiotic prescribing in patients with COVID-19: rapid review and meta-analysis

BJ Langford, M So, S Raybardhan, V Leung…�- Clinical microbiology�…, 2021 - Elsevier
Background The proportion of patients infected with SARS-CoV-2 that are prescribed
antibiotics is uncertain, and may contribute to patient harm and global antibiotic resistance�…

Effect of an inactivated vaccine against SARS-CoV-2 on safety and immunogenicity outcomes: interim analysis of 2 randomized clinical trials

S Xia, K Duan, Y Zhang, D Zhao, H Zhang, Z Xie, X Li…�- Jama, 2020 - jamanetwork.com
Importance A vaccine against coronavirus disease 2019 (COVID-19) is urgently needed.
Objective To evaluate the safety and immunogenicity of an investigational inactivated whole�…

Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial

L Li, W Zhang, Y Hu, X Tong, S Zheng, J Yang, Y Kong…�- Jama, 2020 - jamanetwork.com
Importance Convalescent plasma is a potential therapeutic option for patients with
coronavirus disease 2019 (COVID-19), but further data from randomized clinical trials are�…

[HTML][HTML] Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

WS Lee, AK Wheatley, SJ Kent, BJ DeKosky�- Nature microbiology, 2020 - nature.com
Antibody-based drugs and vaccines against severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) are being expedited through preclinical and clinical development. Data�…