Glutamate is the brain's main excitatory neurotransmitter. Glutamatergic neurons primarily
compose basic neuronal networks, especially in the cortex. An imbalance of excitatory and�…

Alzheimer's disease and epilepsy are common nervous system diseases in older adults, and
their incidence rates tend to increase with age. Patients with mild cognitive impairment and�…

Epilepsy is a prevalent and severe neurological disorder and generally requires prolonged
electrode implantation and tether brain stimulation in refractory cases. However, implants�…

Temporal lobe epilepsy (TLE) is nowadays considered a network disorder impacting several
cognitive domains. In this work we investigated dynamic network reconfiguration differences�…

In recent years, air pollution has garnered global attention due to its ability to traverse
borders and regions, thereby impacting areas far removed from the emission sources. While�…

Importance Epilepsy has been associated with cognitive impairment and potentially
dementia in older individuals. However, the extent to which epilepsy may increase dementia�…

Abstract Perampanel (PER), a novel 3rd-generation antiseizure drug that modulates altered
post-synaptic glutamatergic storming by selectively inhibiting AMPA receptors, is recently�…

Objective To assess the effectiveness and tolerability of brivaracetam (BRV) in adults with
epilepsy by specific comorbidities and epilepsy etiologies. Methods EXPERIENCE/EPD332�…

Purpose This study was to explore whether Ginkgo biloba extract (GBE) improve memory
impairment by alleviating neuroinflammation signaling in mice with status epilepticus�…

Cannabidiol (CBD) is one of the major phytocannabinoids present in the cannabis plant,
with no acute psychotropic effects and a favorable safety and abuse liability profile. Animal�…