Mapping human brain function is a long-standing goal of neuroscience that promises to
inform the development of new treatments for brain disorders. Early maps of human brain�…

Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current�…

The human orbitofrontal cortex, ventromedial prefrontal cortex (vmPFC), and anterior
cingulate cortex are involved in reward processing and thereby in emotion but are also�…

Deep brain stimulation has been extensively studied as a therapeutic option for treatment-
resistant depression (TRD). DBS across different targets is associated with on average 60�…

Neuropsychiatric abnormalities may be broadly divided in two categories: disorders of
mood, affect, and behavior and abnormalities affecting cognition. Among these conditions�…

The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain�…

Resilience in the face of major life stressors is changeable over time and with experience.
Accordingly, differing sets of neurobiological factors may contribute to an adaptive stress�…

Depression associated with traumatic brain injury (TBI) is believed to be clinically distinct
from primary major depressive disorder (MDD) and may be less responsive to conventional�…

Deep brain stimulation is an effective treatment for Parkinson's disease but can be
complicated by side-effects such as cognitive decline. There is often a delay before this side�…

Depression is a common mental disorder characterized by heterogeneous cognitive and
behavioral symptoms. The emerging research paradigm of functional connectomics has�…