[HTML][HTML] Sensorineural hearing loss and cognitive impairment: three hypotheses

H Zhao, Y Wang, L Cui, H Wang, S Liu…�- Frontiers in Aging�…, 2024 - frontiersin.org
Sensorineural hearing loss (SNHL) is a category of hearing loss that often leads to difficulty
in understanding speech and other sounds. Auditory system dysfunction, including deafness�…

Modeling the Interictal Epileptic State for Therapeutic Development with Tetanus Toxin

F Eslami, A Djedovic, JA Loeb�- Brain Sciences, 2024 - mdpi.com
Focal forms of epilepsy can result from a wide range of insults and can vary from focal
symptoms to generalized convulsions. Most drugs that have been developed for epilepsy�…

Immature Status Epilepticus Alters the Temporal Relationship between Hippocampal Interictal Epileptiform Discharges and High-frequency Oscillations

K Kalogeropoulos, C Psarropoulou�- Neuroscience, 2024 - Elsevier
The aim was to investigate the long-term effects of a single episode of immature Status
Epilepticus (SE) on the excitability of the septal and temporal hippocampus in vitro, by�…

Nocturnal synchronization between hippocampal ripples and cortical delta power is a biomarker of hippocampal epileptogenicity

T Iwata, T Yanagisawa, R Fukuma, Y Ikegaya…�- medRxiv, 2024 - medrxiv.org
Objective: Hippocampal ripples are biomarkers of epileptogenicity in patients with epilepsy,
and physiological features characterize memory function in healthy individuals�…

[HTML][HTML] Epilepsy and Encephalopathy

TT Sands, JN Gelinas�- Pediatric Neurology, 2024 - pedneur.com
Background Epilepsy encompasses more than the predisposition to unprovoked seizures. In
children, epileptic activity during (ictal) and between (interictal) seizures has the potential to�…

[HTML][HTML] Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease

E Chartampila, KS Elayouby, P Leary, JJ LaFrancois…�- eLife, 2024 - elifesciences.org
Maternal choline supplementation (MCS) improves cognition in Alzheimer's disease (AD)
models. However, the effects of MCS on neuronal hyperexcitability in AD are unknown. We�…

Single neuron and population spiking dynamics in physiologic and pathologic memory processing

AR Hassan - 2024 - academiccommons.columbia.edu
Cognitive processes in the human brain are mediated by complex interactions among
distributed brain regions. The interaction between the hippocampus and neocortical regions�…

The Impact of Interictal Epileptiform Discharges (IEDs) on Synaptic Plasticity: Implications for Memory Dysfunction in Epilepsy

LH Zukowski - 2024 - rave.ohiolink.edu
Beyond seizures themselves, individuals with epilepsy commonly grapple with cognitive
comorbidities, with memory impairment being most prominent. Despite ongoing investigative�…