[HTML][HTML] The role of microRNA in the pathogenesis of diabetic nephropathy
J Szostak, A Gorący, D Durys, P Dec…�- International Journal of�…, 2023 - mdpi.com
Diabetic nephropathy is one of the most common and severe complications of diabetes
mellitus, affecting one in every five patients suffering from diabetes. Despite extensive�…
mellitus, affecting one in every five patients suffering from diabetes. Despite extensive�…
[HTML][HTML] p53 and myofibroblast apoptosis in organ fibrosis
K McElhinney, M Irnaten, C O'Brien�- International Journal of Molecular�…, 2023 - mdpi.com
Organ fibrosis represents a dysregulated, maladaptive wound repair response that results in
progressive disruption of normal tissue architecture leading to detrimental deterioration in�…
progressive disruption of normal tissue architecture leading to detrimental deterioration in�…
[HTML][HTML] N6-methyladenosine RNA methylation in diabetic kidney disease
J Huang, F Yang, Y Liu, Y Wang�- Biomedicine & Pharmacotherapy, 2024 - Elsevier
Diabetic kidney disease (DKD) is a major microvascular complication of diabetes, and
hyperglycemic memory associated with diabetes carries the risk of disease occurrence�…
hyperglycemic memory associated with diabetes carries the risk of disease occurrence�…
SEMA7a primes integrin α5β1 engagement instructing fibroblast mechanotransduction, phenotype and transcriptional programming
Integrins are cellular receptors that bind the extracellular matrix (ECM) and facilitate the
transduction of biochemical and biophysical microenvironment cues into cellular responses�…
transduction of biochemical and biophysical microenvironment cues into cellular responses�…
Irisin ameliorates diabetic kidney disease by restoring autophagy in podocytes
W Lai, D Luo, Y Li, Y Li, Q Wang, Z Hu, Z Ye…�- The FASEB�…, 2023 - Wiley Online Library
Many studies have highlighted the importance of moderate exercise. While it can attenuate
diabetic kidney disease, its mechanism has remained unclear. The level of myokine irisin in�…
diabetic kidney disease, its mechanism has remained unclear. The level of myokine irisin in�…
[HTML][HTML] Long non-coding RNA lncMGC mediates the expression of TGF-β-induced genes in renal cells via nucleosome remodelers
Background: MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play key roles in
diabetic kidney disease (DKD). The miR-379 megacluster of miRNAs and its host transcript�…
diabetic kidney disease (DKD). The miR-379 megacluster of miRNAs and its host transcript�…
MicroRNA-217-5p triggers dopaminergic neuronal degeneration via autophagy activation under Atrazine exposure
B Li, Y Jiang, T Wang, W Liu, X Chen, J He, Z Du…�- Environmental�…, 2024 - Elsevier
Atrazine (ATR) is a widely used agricultural herbicide, and its accumulation in soil and water
can cause various environmental health problems. ATR has neurotoxic effects on�…
can cause various environmental health problems. ATR has neurotoxic effects on�…
[HTML][HTML] Luteolin improves nephropathy in hyperglycemic rats through anti-oxidant, anti-inflammatory, and anti-apoptotic mechanisms
LY Chen, HL Cheng, CK Liao, YH Kuan…�- Journal of Functional�…, 2023 - Elsevier
Hyperglycemia can also induce the production of free radicals and the progression of
inflammatory reactions. The aim of this study is to explore the potential anti-oxidant and anti�…
inflammatory reactions. The aim of this study is to explore the potential anti-oxidant and anti�…
[HTML][HTML] Identification of altered miRNAs and their targets in placenta accreta
JM Murrieta-Coxca, E Barth…�- Frontiers in�…, 2023 - frontiersin.org
Placenta accreta spectrum (PAS) is one of the major causes of maternal morbidity and
mortality worldwide with increasing incidence. PAS refers to a group of pathological�…
mortality worldwide with increasing incidence. PAS refers to a group of pathological�…
The exciting future for scleroderma: what therapeutic pathways are on the horizon?
JHW Distler, G Riemekasten…�- Rheumatic Disease�…, 2023 - rheumatic.theclinics.com
There has been major progress in understanding pathogenic mechanisms in systemic
sclerosis (SSc) at a molecular and cellular level. This has permitted key pathways�…
sclerosis (SSc) at a molecular and cellular level. This has permitted key pathways�…