[HTML][HTML] Cellular Red-Ox system in health and disease: The latest update

AB Jena, RR Samal, NK Bhol, AK Duttaroy�- Biomedicine &�…, 2023 - Elsevier
Cells are continually exposed to reactive oxygen species (ROS) generated during cellular
metabolism. Apoptosis, necrosis, and autophagy are biological processes involving a�…

Ascorbic acid modulates immune responses through Jumonji‐C domain containing histone demethylases and Ten eleven translocation (TET) methylcytosine�…

J Maity, S Majumder, R Pal, B Saha…�- …, 2023 - Wiley Online Library
Ascorbic acid is a redox regulator in many physiological processes. Besides its antioxidant
activity, many intriguing functions of ascorbic acid in the expression of immunoregulatory�…

Ascorbate and its transporter SVCT2: The dynamic duo's integrated roles in CNS neurobiology and pathophysiology

CC Portugal�- Free Radical Biology and Medicine, 2024 - Elsevier
Ascorbate is a small antioxidant molecule essential for the proper development and function
of the brain. Ascorbate is transported into the brain and between brain cells via the Sodium�…

[HTML][HTML] Structure, mechanism, and evolution of the last step in vitamin C biosynthesis

A Boverio, N Jamil, B Mannucci, ML Mascotti…�- Nature�…, 2024 - nature.com
Photosynthetic organisms, fungi, and animals comprise distinct pathways for vitamin C
biosynthesis. Besides this diversity, the final biosynthetic step consistently involves an�…

[HTML][HTML] Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter

M Wang, J He, S Li, Q Cai, K Zhang, J She�- Nature Communications, 2023 - nature.com
Vitamin C (L-ascorbic acid) is an essential nutrient for human health, and its deficiency has
long been known to cause scurvy. Sodium-dependent vitamin C transporters (SVCTs) are�…

[HTML][HTML] Estimating Vitamin C Intake Requirements in Diabetes Mellitus: Analysis of NHANES 2017–2018 and EPIC-Norfolk Cohorts

AC Carr, H Lunt, NJ Wareham, PK Myint�- Antioxidants, 2023 - mdpi.com
Vitamin C is an essential enzyme cofactor and antioxidant with pleiotropic roles in human
physiology. Circulating vitamin C concentrations are lower in people with diabetes mellitus�…

QTL analysis for ascorbic acid content in strawberry fruit reveals a complex genetic architecture and association with GDP-L-galactose phosphorylase

P Mu�oz, C Castillejo, JA G�mez, L Miranda…�- Horticulture�…, 2023 - academic.oup.com
Strawberry (Fragaria� ananassa) fruits are an excellent source of L-ascorbic acid (AsA), a
powerful antioxidant for plants and humans. Identifying the genetic components underlying�…

[HTML][HTML] Dimeric transport mechanism of human vitamin C transporter SVCT1

TA Kobayashi, H Shimada, FK Sano, Y Itoh…�- Nature�…, 2024 - nature.com
Vitamin C plays important roles as a cofactor in many enzymatic reactions and as an
antioxidant against oxidative stress. As some mammals including humans cannot synthesize�…

Effect of popping and malting processing techniques on physiochemical, antinutrients and antioxidant properties of millets flour

H Kaur, HK Oberoi, KN Ganapathy…�- Journal of Food Science�…, 2023 - Springer
The present investigation aimed to evaluate the effect of popping and malting on nutritional
characteristics in millets. Five genotypes each of sorghum, finger millet and pearl millet were�…

Cysteine enrichment mediates co-option of uricase in reptilian skin and transition to uricotelism

G Mori, A Liuzzi, L Ronda, M Di Palma…�- Molecular Biology�…, 2023 - academic.oup.com
Uric acid is the main means of nitrogen excretion in uricotelic vertebrates (birds and reptiles)
and the end product of purine catabolism in humans and a few other mammals. While�…