Sensorineural hearing loss (SNHL) is a category of hearing loss that often leads to difficulty
in understanding speech and other sounds. Auditory system dysfunction, including deafness�…

How the development and function of neural circuits governing learning and memory are
affected by insults in early life remains poorly understood. The goal of this study was to�…

Background and Objectives To investigate the spatiotemporal characteristics of sleep
waveforms in temporal lobe epilepsy (TLE) and examine their association with cognition�…

Focal forms of epilepsy can result from a wide range of insults and can vary from focal
symptoms to generalized convulsions. Most drugs that have been developed for epilepsy�…

Interictal spikes (IIS) are a common type of abnormal electrical activity in Alzheimer's
disease (AD) and preclinical models. The brain regions where IIS are largest are not known�…

Temporal lobe epilepsy (TLE) is characterized by spontaneous recurrent seizures, abnormal
activity between seizures, and impaired behavior. CA2 pyramidal neurons (PNs) are�…

The aim was to investigate the long-term effects of a single episode of immature Status
Epilepticus (SE) on the excitability of the septal and temporal hippocampus in vitro, by�…

Objective Cognitive impairment often impacts quality of life in epilepsy even if seizures are
controlled. Word‐finding difficulty is particularly prevalent and often attributed to etiological�…

Animal and human studies have shown that the seizure-generating region is vastly
dependent on distant neuronal hubs that can decrease duration and propagation of ongoing�…

Background Epilepsy encompasses more than the predisposition to unprovoked seizures. In
children, epileptic activity during (ictal) and between (interictal) seizures has the potential to�…