Clinical Management of Brugada Syndrome: Commentary From the Experts

MJ Cutler, LL Eckhardt, ES Kaufman…�- Circulation�…, 2024 - Am Heart Assoc
Although there is consensus on the management of patients with Brugada Syndrome with
high risk for sudden cardiac arrest, asymptomatic or intermediate-risk patients present�…

Anti-cocaine vaccine development: Where are we now and where are we going?

RJ Stephenson, I Toth�- Journal of Medicinal Chemistry, 2023 - ACS Publications
Cocaine is one of the oldest and most widely used illicit drugs in the world and is
responsible for major worldwide medical and social problems. Drug addiction is a disease�…

[HTML][HTML] Cocaine and ischemic or hemorrhagic stroke: a systematic review and meta-analysis of clinical evidence

LF Rendon, S Malta, J Leung, R Badenes…�- Journal of Clinical�…, 2023 - mdpi.com
Cocaine consumption has increased over the last decade. The potent sympathomimetic
effects of the drug can lead to serious neurovascular complications in the form of ischemic�…

Severe biventricular cardiomyopathy in both current and former long-term users of anabolic–androgenic steroids

R Abdullah, A Bj�rnebekk, LE Hauger…�- European Journal of�…, 2024 - academic.oup.com
Aims This study aims to explore the cardiovascular effects of long-term anabolic–androgenic
steroid (AAS) use in both current and former weightlifting AAS users and estimate the�…

[HTML][HTML] cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement

L Mu, X Liu, H Yu, CR Vickstrom, V Friedman…�- Molecular�…, 2023 - nature.com
Chronic cocaine exposure induces enduring neuroadaptations that facilitate motivated drug
taking. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are known to�…

Prevalence of unhealthy substance use and associated characteristics among patients presenting for surgery

AC Fernandez, JF Waljee, V Gunaseelan…�- Annals of�…, 2023 - journals.lww.com
Objective: To assess the prevalence of and identify characteristics associated with unhealthy
use before surgery. Background: Although the escalation in US drug overdose deaths is�…

Substance use in pregnancy and its association with cardiovascular events

K Evans, P Wu, MA Mamas, C Irwin, P Kang, JH Perlow…�- JACC: Advances, 2023 - jacc.org
Background Substance use and cardiovascular (CV) events are increasing among pregnant
women in the United States, but association between substance use in pregnancy and CV�…

Elevated interleukin 8 and matrix metalloproteinase 9 levels are associated with myocardial pathology in users of anabolic-androgenic steroids

I Gregersen, ME Scarth, R Abdullah…�- European Journal of�…, 2024 - academic.oup.com
Aims In the current paper, we aim to explore the effect of both current and former long-term
anabolic-androgenic steroid (AAS) use on regulation of systemic inflammatory markers and�…

Perceived barriers and facilitators to health behaviors in European childhood cancer survivors: A qualitative PanCareFollowUp study

E Bouwman, SMF Pluijm, I Stollman…�- Cancer�…, 2023 - Wiley Online Library
Background Healthy behaviors, that is, engaging in regular physical activities, maintaining a
healthy diet, limiting alcohol consumption, and avoiding tobacco and drug use, decrease the�…

[HTML][HTML] Exercise Modifies the Brain Metabolic Response to Chronic Cocaine Exposure Inhibiting the Stria Terminalis

C Hanna, R Yao, M Sajjad, M Gold, K Blum, PK Thanos�- Brain Sciences, 2023 - mdpi.com
It is well known that exercise promotes health and wellness, both mentally and
physiologically. It has been shown to play a protective role in many diseases, including�…