Engineering the composition and fate of wild populations with gene drive

BA Hay, G Oberhofer, M Guo�- Annual Review of Entomology, 2021 - annualreviews.org
Insects play important roles as predators, prey, pollinators, recyclers, hosts, parasitoids, and
sources of economically important products. They can also destroy crops; wound animals;
and serve as vectors for plant, animal, and human diseases. Gene drive—a process by
which genes, gene complexes, or chromosomes encoding specific traits are made to spread
through wild populations, even if these traits result in a fitness cost to carriers—provides new
opportunities for altering populations to benefit humanity and the environment in ways that�…
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