The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study recruited
3624 pregnant women, most partners and 3542 eligible offspring. We hypothesise that early�…

Background This paper describes the background, aim, and design of a prospective birth-
cohort study in Korea called the COhort for Childhood Origin of Asthma and allergic�…

Background It is hypothesised that complex interactions between genetic and environmental
factors give rise to allergy and asthma in childhood. The C anadian H ealthy I nfant L�…

Abstract The Canadian Healthy Infant Longitudinal Development birth cohort was designed
to elucidate interactions between environment and genetics underlying development of�…

Long-term birth cohort studies are essential to understanding the life course and childhood
predictors of allergy and the complex interplay between genes and the environment�…

Childhood asthma develops from a complex interaction among host and environmental
factors in early life. Birth cohort studies have provided valuable insight into asthma risk�…

Population-based birth cohorts on asthma and allergies increasingly provide new insights
into the development and natural history of the diseases. More than 130 birth cohorts�…

Background We hypothesize that perinatal exposures, in particular the human microbiome
and maternal nutrition during pregnancy, interact with the genetic predisposition to cause an�…

The developmental origins of health and disease hypothesis suggests that a child's
environment from conception to 1000 days greatly influences the child's risk for chronic�…

The importance of early life environmental influences on the aetiology of asthma is implied
by the observed geographic and temporal variation in the prevalence of the disease among�…