Current consensus holds that a single medullary network generates respiratory rhythm in
mammals. Pre-B�tzinger Complex inspiratory (I) neurons, isolated in transverse slices, and�…

Breathing in mammals is a seemingly straightforward behaviour controlled by the brain. A
brainstem nucleus called the preB�tzinger Complex sits at the core of the neural circuit�…

Breathing emerges through complex network interactions involving neurons distributed
throughout the nervous system. The respiratory rhythm generating network is composed of�…

The preB�tzinger Complex (preB�tC), a medullary network critical for breathing, relies on
excitatory interneurons to generate the inspiratory rhythm. Yet, half of preB�tC neurons are�…

Breathing is vital for survival but also interesting from the perspective of rhythm generation.
This rhythmic behavior is generated within the brainstem and is thought to emerge through�…

Many networks generate distinct rhythms with multiple frequency and amplitude
characteristics. The respiratory network in the pre-Bötzinger complex (pre-Böt) generates�…

The cellular and circuit mechanisms generating the rhythm of breathing in mammals have
been under intense investigation for decades. Here, we try to integrate the key discoveries�…

Respiratory rhythm generation depends on a complex interaction between synaptic and
membrane properties of functionally defined neurons. To gain a better understanding of how�…

In the mammalian respiratory central pattern generator, the preB�tzinger complex (preB�tC)
produces rhythmic bursts that drive inspiratory motor output. Cellular mechanisms initiated�…

Shao, Xuesi M. and Jack L. Feldman. Respiratory rhythm generation and synaptic inhibition
of expiratory neurons in pre-Bötzinger complex: differential roles of glycinergic and�…