Background Evidence suggests maternal pregnancy dietary intake and nutrition in the early
postnatal period to be of importance for the newborn child's health. However, studies�…

Background The intestinal metabolome reflects the biological consequences of diverse
exposures and might provide insight into asthma pathophysiology. Objective We sought to�…

Allergy is one of the most common diseases among young children yet all factors that affect
development of allergy remain unclear. In a small cohort of 65 children living in the same�…

The in utero environment during pregnancy has important implications for the developing
health of the child. We aim to examine the potential impact of maternal metabolome at two�…

The pregnancy period and first days of a newborn's life is an important time window to
ensure a healthy development of the baby. This is also the time when the mother and her�…

Asthma, allergic rhinitis, food allergy, and atopic dermatitis are common childhood diseases
with several different underlying mechanisms, ie, endotypes of disease. Metabolomics has�…

Because asthma is a disease that results from host-environment interactions, an approach
that allows assessment of the effect of the environment on the host is needed to understand�…

Background Intestinal microenvironmental perturbations may increase food allergy risk. We
hypothesize that children with clinical food allergy, those with food sensitization, and healthy�…

Urine metabolomics case-control studies of childhood asthma have demonstrated a
discriminative ability. Here, we investigated whether urine metabolic profiles from healthy�…

Background Prematurity is a severe pathophysiological condition, however, little is known
about the gestational age-dependent development of the neonatal metabolome. Methods�…