Localizing human brain functions is a long-standing goal in systems neuroscience. Toward
this goal, neuroimaging studies have traditionally used volume-based smoothing, registered�…

The macro-connectome elucidates the pathways through which brain regions are
structurally connected or functionally coupled to perform a specific cognitive task. It�…

Regional specialization and functional integration are often viewed as two fundamental
principles of human brain organization. They are closely intertwined because each�…

The cerebral cortex in mammals contains a mosaic of cortical areas that differ in function,
architecture, connectivity, and/or topographic organization. A combination of local�…

Previous studies demonstrated substantial variability of the location of primary visual cortex
(V1) in stereotaxic coordinates when linear volume-based registration is used to match�…

Group analysis of structure or function in cerebral cortex typically involves, as a first step, the
alignment of cortices. A surface-based approach to this problem treats the cortex as a�…

One of the most specific but also challenging properties of the brain is its topographic
organization into distinct modules or cortical areas. In this paper, we first review the concept�…

The study of stroke patients with modern lesion-symptom analysis techniques has yielded
valuable insights into the representation of spatial attention in the human brain. Here we�…

Being able to detect reliably functional activity in a population of subjects is crucial in human
brain mapping, both for the understanding of cognitive functions in normal subjects and for�…

The core concept within the field of brain mapping is the use of a standardized, or
“stereotaxic”, 3D coordinate frame for data analysis and reporting of findings from�…