Inspiratory and sigh breathing rhythms depend on distinct cellular signalling mechanisms in the preB�tzinger complex
DS Borrus, MK Stettler, CJ Grover…�- The Journal of�…, 2024 - Wiley Online Library
Breathing behaviour involves the generation of normal breaths (eupnoea) on a timescale of
seconds and sigh breaths on the order of minutes. Both rhythms emerge in tandem from a�…
seconds and sigh breaths on the order of minutes. Both rhythms emerge in tandem from a�…
Generation and maintenance of the respiratory rhythm
DW Richter�- Journal of Experimental Biology, 1982 - journals.biologists.com
Activities of the phrenic and internal intercostal nerves show that the central nervous rhythm
of respiration consists of 3 phases: inspiratory, postinspiratory and expiratory. The discharge�…
of respiration consists of 3 phases: inspiratory, postinspiratory and expiratory. The discharge�…
[HTML][HTML] Respiratory rhythm generation: triple oscillator hypothesis
TM Anderson, JM Ramirez�- F1000Research, 2017 - ncbi.nlm.nih.gov
Breathing is vital for survival but also interesting from the perspective of rhythm generation.
This rhythmic behavior is generated within the brainstem and is thought to emerge through�…
This rhythmic behavior is generated within the brainstem and is thought to emerge through�…
[HTML][HTML] C1 neurons are part of the circuitry that recruits active expiration in response to the activation of peripheral chemoreceptors
Breathing results from the interaction of two distinct oscillators: the pre-B�tzinger Complex
(preB�tC), which drives inspiration; and the lateral parafacial region (pFRG), which drives�…
(preB�tC), which drives inspiration; and the lateral parafacial region (pFRG), which drives�…
[CITATION][C] Graded inspiratory inhibition: the first stage of inspiratory “off-switching”
JE Remmers, JP Baker Jr…�- Central nervous�…, 1979 - Pergamon Press New York
Networks within networks: the neuronal control of breathing
AJ Garcia III, S Zanella, H Koch, A Doi…�- Progress in brain�…, 2011 - Elsevier
Breathing emerges through complex network interactions involving neurons distributed
throughout the nervous system. The respiratory rhythm generating network is composed of�…
throughout the nervous system. The respiratory rhythm generating network is composed of�…
Degeneracy as a substrate for respiratory regulation
NM Mellen�- Respiratory physiology & neurobiology, 2010 - Elsevier
Recent studies in vivo and in vitro suggest that both respiratory rhythmogenesis and its
central chemosensory modulation arise from multiple, mechanistically and/or anatomically�…
central chemosensory modulation arise from multiple, mechanistically and/or anatomically�…
[HTML][HTML] Organization of the core respiratory network: insights from optogenetic and modeling studies
J Ausborn, H Koizumi, WH Barnett…�- PLoS computational�…, 2018 - journals.plos.org
The circuit organization within the mammalian brainstem respiratory network, specifically
within and between the pre-B�tzinger (pre-B�tC) and B�tzinger (B�tC) complexes, and the�…
within and between the pre-B�tzinger (pre-B�tC) and B�tzinger (B�tC) complexes, and the�…
Hypercapnic and hypoxic responses require intact neural transmission from the pre-B�tzinger complex
M Wu, MA Haxhiu, SM Johnson�- Respiratory physiology & neurobiology, 2005 - Elsevier
The central respiratory network that includes the pre-B�tzinger complex (pre-B�tC), a region
believed to contain rhythmogenic neurons, is capable of responding to fluctuations in CO2�…
believed to contain rhythmogenic neurons, is capable of responding to fluctuations in CO2�…
The role of spiking and bursting pacemakers in the neuronal control of breathing
Breathing is controlled by a distributed network involving areas in the neocortex, cerebellum,
pons, medulla, spinal cord, and various other subcortical regions. However, only one area�…
pons, medulla, spinal cord, and various other subcortical regions. However, only one area�…