[HTML][HTML] Status Epilepticus Induced Spontaneous Dentate Gyrus Spikes: In Vivo Current Source Density Analysis

SP Flynn, S Barrier, RC Scott, PP Lenck-Santini…�- PLoS�…, 2015 - journals.plos.org
The dentate gyrus is considered to function as an inhibitory gate limiting excitatory input to
the hippocampus. Following status epilepticus (SE), this gating function is reduced and�…

[HTML][HTML] Functional and morphological changes in the dentate gyrus after experimental status epilepticus

J Matzen, K Buchheim, FKH van Landeghem…�- Seizure, 2008 - Elsevier
Status epilepticus may cause long-term functional and structural consequences possibly
resulting in brain dysfunctions such as chronic epilepsy. In epileptogenesis, the dentate�…

Hippocampal responses to electrical stimulation of the major input pathways are modulated by dentate spikes

SM Lehtonen, T Waselius, M Penttonen…�- …, 2022 - Wiley Online Library
Dentate gyrus (DG) is important for pattern separation and spatial memory, and it is thought
to gate information flow to the downstream hippocampal subregions. Dentate spikes (DSs)�…

[HTML][HTML] Disentangling chemical and electrical effects of status epilepticus-induced dentate gyrus abnormalities

DMS Moura, IRP de Sales, JA Brand�o, MR Costa…�- Epilepsy & Behavior, 2021 - Elsevier
In rodents, status epilepticus (SE) triggered by chemoconvulsants can differently affect the
proliferation and fate of adult-born dentate granule cells (DGCs). It is unknown whether�…

Immature Status Epilepticus Alters the Temporal Relationship between Hippocampal Interictal Epileptiform Discharges and High-frequency Oscillations

K Kalogeropoulos, C Psarropoulou�- Neuroscience, 2024 - Elsevier
The aim was to investigate the long-term effects of a single episode of immature Status
Epilepticus (SE) on the excitability of the septal and temporal hippocampus in vitro, by�…

Differential and long‐lasting alterations of high‐voltage activated calcium currents in CA1 and dentate granule neurons after status epilepticus

JA Gorter, AJ Borgdorff, EA Van Vliet…�- European Journal of�…, 2002 - Wiley Online Library
The effects on high‐voltage activated (HVA) calcium currents were examined in
hippocampal CA1 cells and dentate gyrus (DG) granule neurons, 2 days (short‐term; ST)�…

Long-duration self-sustained epileptiform activity in the hippocampal-parahippocampal slice: a model of status epilepticus

A Rafiq, YF Zhang, RJ DeLorenzo…�- Journal of�…, 1995 - journals.physiology.org
1. Combined hippocampal-parahippocampal slices were employed to study the
development of complex epileptiform discharges after Schaeffer collateral stimulation in�…

Increased persistent sodium currents in rat entorhinal cortex layer V neurons in a post–status epilepticus model of temporal lobe epilepsy

N Agrawal, A Alonso, DS Ragsdale�- Epilepsia, 2003 - Wiley Online Library
Purpose: Spontaneous seizures in rats emerge several weeks after induction of status
epilepticus with pharmacologic treatment or electrical stimulation, providing an animal�…

Transient loss of inhibition precedes spontaneous seizures after experimental status epilepticus

M Holtkamp, J Matzen, F Van Landeghem…�- Neurobiology of�…, 2005 - Elsevier
The pathophysiological mechanisms that cause spontaneous seizures following status
epilepticus are largely unknown. Erosion of inhibition is regarded as an important�…

Generation and propagation of epileptiform discharges in a combined entorhinal cortex/hippocampal slice

A Rafiq, RJ DeLorenzo…�- Journal of�…, 1993 - journals.physiology.org
1. The development of epileptiform discharges in response to tetanic stimulation of the
Schaeffer collaterals was studied by using extracellular field potential recordings in CA1�…