The inhibin/activin family and ovarian cancer
HG Burger, PJ Fuller�- Trends in Endocrinology & Metabolism, 1996 - cell.com
Ovarian cancer is the most common fatal malignancy of the female reproductive tract and
frequently presents at an advanced stage. There is, thus, a great need for more sensitive�…
frequently presents at an advanced stage. There is, thus, a great need for more sensitive�…
Inhibins/activins as diagnostic markers for ovarian cancer
DM Robertson, T Stephenson, E Pruysers…�- Molecular and Cellular�…, 2002 - Elsevier
It is widely recognised that the early detection and subsequent assessment of recurrence of
ovarian cancers are key steps for successful treatment. Available serum markers (eg CA125)�…
ovarian cancers are key steps for successful treatment. Available serum markers (eg CA125)�…
Inhibins and ovarian cancer
DM Robertson, E Pruysers, HG Burger, T Jobling…�- Molecular and cellular�…, 2004 - Elsevier
The inhibins are produced and secreted by several ovarian cancers. Monitoring serum
levels by immunoassay may be a useful diagnostic aid in the initial assessment of this�…
levels by immunoassay may be a useful diagnostic aid in the initial assessment of this�…
Inhibin as a diagnostic marker for ovarian cancer
DM Robertson, E Pruysers, T Jobling�- Cancer letters, 2007 - Elsevier
The inhibins are a family of growth factors comprised of several different species that are
secreted in the female principally from the ovarian follicle. The inhibins perform best as�…
secreted in the female principally from the ovarian follicle. The inhibins perform best as�…
Inhibin and activin are demonstrable by immunohistochemistry in ovarian tumor tissue
CJ Gurusinghe, DL Healy, T Jobling, P Mamers…�- Gynecologic�…, 1995 - Elsevier
Elevated serum immunoreactive inhibin concentrations have been reported in patients with
mucinous and granulosa cell tumors of the ovary. The present study aimed to determine�…
mucinous and granulosa cell tumors of the ovary. The present study aimed to determine�…
Serum inhibin, activin and follistatin in postmenopausal women with epithelial ovarian carcinoma
Objective To investigate the role of serum inhibin A, inhibin pro‐αC immunoreactivity, activin
A, and follistatin in postmenopausal women with epithelial ovarian cancer. Design Case�…
A, and follistatin in postmenopausal women with epithelial ovarian cancer. Design Case�…
[PDF][PDF] Is inhibin a serum marker for ovarian cancer?
GM Lambert-Messerlian�- European journal of endocrinology, 2000 - Citeseer
Research endocrinologists are well aware of inhibin and the family of proteins of which it is a
part. Inhibin was discovered almost 70 years ago as a product of the gonads that selectively�…
part. Inhibin was discovered almost 70 years ago as a product of the gonads that selectively�…
The inhibins and ovarian cancer
HG Burger, PJ Fuller, S Chu, P Mamers…�- Molecular and cellular�…, 2001 - Elsevier
Interest in inhibin as a marker of ovarian malignancy was stimulated by the description of
elevated immunoreactive inhibin levels in the sera of patients with granulosa cell tumours�…
elevated immunoreactive inhibin levels in the sera of patients with granulosa cell tumours�…
Inhibin subunit gene expression in ovarian cancer
PJ Fuller, S Chu, T Jobling, P Mamers, DL Healy…�- Gynecologic�…, 1999 - Elsevier
Objective (s). Granulosa cell tumors (GCT) and mucinous cystadenocarcinoma of the ovary
are associated with elevated circulating levels of immunoreactive inhibin. Measurement of�…
are associated with elevated circulating levels of immunoreactive inhibin. Measurement of�…
Inhibin and ovarian cancer
HG Burger, A Baillie, AE Drummond, DL Healy…�- Journal of reproductive�…, 1998 - Elsevier
Previous observations from our laboratory have demonstrated that the levels of
immunoreactive inhibin (ir-inh) are elevated in almost all patients with granulosa cell�…
immunoreactive inhibin (ir-inh) are elevated in almost all patients with granulosa cell�…