The inhibin/activin family and ovarian cancer

HG Burger, PJ Fuller�- Trends in Endocrinology & Metabolism, 1996 - cell.com
Ovarian cancer is the most common fatal malignancy of the female reproductive tract and
frequently presents at an advanced stage. There is, thus, a great need for more sensitive�…

Inhibins/activins as diagnostic markers for ovarian cancer

DM Robertson, T Stephenson, E Pruysers…�- Molecular and Cellular�…, 2002 - Elsevier
It is widely recognised that the early detection and subsequent assessment of recurrence of
ovarian cancers are key steps for successful treatment. Available serum markers (eg CA125)�…

Inhibins and ovarian cancer

DM Robertson, E Pruysers, HG Burger, T Jobling…�- Molecular and cellular�…, 2004 - Elsevier
The inhibins are produced and secreted by several ovarian cancers. Monitoring serum
levels by immunoassay may be a useful diagnostic aid in the initial assessment of this�…

Inhibin as a diagnostic marker for ovarian cancer

DM Robertson, E Pruysers, T Jobling�- Cancer letters, 2007 - Elsevier
The inhibins are a family of growth factors comprised of several different species that are
secreted in the female principally from the ovarian follicle. The inhibins perform best as�…

Inhibin and activin are demonstrable by immunohistochemistry in ovarian tumor tissue

CJ Gurusinghe, DL Healy, T Jobling, P Mamers…�- Gynecologic�…, 1995 - Elsevier
Elevated serum immunoreactive inhibin concentrations have been reported in patients with
mucinous and granulosa cell tumors of the ovary. The present study aimed to determine�…

Serum inhibin, activin and follistatin in postmenopausal women with epithelial ovarian carcinoma

U Menon, SC Riley, J Thomas, C Bose…�- …�Journal of Obstetrics�…, 2000 - Wiley Online Library
Objective To investigate the role of serum inhibin A, inhibin pro‐αC immunoreactivity, activin
A, and follistatin in postmenopausal women with epithelial ovarian cancer. Design Case�…

[PDF][PDF] Is inhibin a serum marker for ovarian cancer?

GM Lambert-Messerlian�- European journal of endocrinology, 2000 - Citeseer
Research endocrinologists are well aware of inhibin and the family of proteins of which it is a
part. Inhibin was discovered almost 70 years ago as a product of the gonads that selectively�…

The inhibins and ovarian cancer

HG Burger, PJ Fuller, S Chu, P Mamers…�- Molecular and cellular�…, 2001 - Elsevier
Interest in inhibin as a marker of ovarian malignancy was stimulated by the description of
elevated immunoreactive inhibin levels in the sera of patients with granulosa cell tumours�…

Inhibin subunit gene expression in ovarian cancer

PJ Fuller, S Chu, T Jobling, P Mamers, DL Healy…�- Gynecologic�…, 1999 - Elsevier
Objective (s). Granulosa cell tumors (GCT) and mucinous cystadenocarcinoma of the ovary
are associated with elevated circulating levels of immunoreactive inhibin. Measurement of�…

Inhibin and ovarian cancer

HG Burger, A Baillie, AE Drummond, DL Healy…�- Journal of reproductive�…, 1998 - Elsevier
Previous observations from our laboratory have demonstrated that the levels of
immunoreactive inhibin (ir-inh) are elevated in almost all patients with granulosa cell�…