For stroke and spinal cord injury, folic acid supplementation has been shown to enhance
neurodevelopment and to provide neuroprotection. We hypothesized that folic acid would�…

Folic acid supplementation has proved to be extremely effective in reducing the occurrence
of neural tube defects (NTDs) and other congenital abnormalities in humans, suggesting that�…

Purpose: Traumatic brain injury (TBI) is a major health concern today and effective
treatments must be developed in order to combat the numerous TBIs that occur each year�…

Increasing neurogenesis may restore cognitive functions that are impaired in ischemia
stroke. Folic acid has been reported to play an important role in neuronal development and�…

Folic acid plays an important role in neuroplasticity and acts as a neuroprotective agent, as
observed in experimental brain ischemia studies. The aim of this study was to investigate the�…

Maternal one-carbon metabolism plays an important role in early life programming. There is
a well-established connection between the fetal environment and the health status of the�…

Cumulative effects of repetitive mild head injury in the pediatric population are unknown. We
have developed a cognitive composite dysfunction score that correlates white matter injury�…

Folates are B-vitamins that play an important role in brain function. Dietary and genetic
deficiencies in folate metabolism result in elevated levels of homocysteine which have been�…

Maternal folate status during pregnancy may influence central nervous system (CNS)
development in offspring. However, the recommended intakes of folic acid for women of�…

Folic acid deficiency increases stroke risk. In the present study, we examined whether folic
acid deficiency enhances neuronal damage and gliosis via oxidative stress in the gerbil�…