Children exposed to various forms of adversity early in life are at increased risk for a broad
range of developmental difficulties, affecting both cognitive and emotional adjustment. We�…

Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing�…

Current frameworks for understanding the link between early adverse childhood
experiences and later negative life outcomes, including psychopathology, focus on the�…

Despite long-standing interest in the influence of adverse early experiences on mental
health, systematic scientific inquiry into childhood adversity and developmental outcomes�…

Human brain development is optimized to learn from environmental cues. The protracted
development of the cortex and its connections with subcortical targets has been argued to�…

The human brain requires a wide variety of experiences and environmental inputs in order
to develop normally. Children who are neglected by caregivers or raised in institutional�…

It is now widely recognized that children exposed to adverse life events in the first years of
life are at increased risk for a variety of neural, behavioral, and psychological sequelae. As�…

Background Childhood maltreatment is one of the most important preventable risk factors for
a wide variety of psychiatric disorders. Further, when psychiatric disorders emerge in�…

A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental�…

Exposure to childhood adversity is common and a powerful risk factor for many forms of
psychopathology. In this opinion piece, we argue for greater translation of knowledge about�…