Ischemia-reperfusion (I/R) injury occurs as a result of restoring blood flow to previously
hypoperfused vessels or after tissue transplantation and is characterized by inflammation�…

Hepatic ischemia reperfusion (IR) injury is a major clinical problem during the perioperative
period and occurs frequently after major hepatic resection or liver transplantation�…

Ischemia reperfusion injury results from tissue damage during ischemia and ongoing
inflammation and injury during reperfusion. Liver reperfusion injury is reduced by�…

Activation of the A 2A adenosine receptor (A 2A R) during reperfusion of various tissues has
been found to markedly reduce ischemia-reperfusion injury. In this study, we used bone�…

To examine whether adenosine reduces ischemia/reperfusion (I/R)-induced liver injury by
inhibiting leukocyte activation via A2receptor (A2R) stimulation, we investigated the effects�…

Background Liver ischemia-reperfusion injury (IRI) is a known risk factor for the
postoperative outcome of patients undergoing liver surgery/transplantation. Attempts to�…

Gastrointestinal ischemia/reperfusion (IR) injury significantly contributes to the morbidity and
mortality of critical illness. In this study, we hypothesized a protective role for extracellular�…

A2A adenosine receptors (A2A-ARs) are known modulators of renal hemodynamics and
potent inhibitors of inflammation. We sought to determine whether selective activation of A2A�…

A3 adenosine receptors (A3ARs) have been implicated in regulating mast cell function and
in cardioprotection during ischemia-reperfusion injury. The physiological role of A3ARs is�…

Whole body exposure of wild type control littermates and A2A adenosine receptor (A2AR)
gene deleted mice to low oxygen containing inspired gas mixture allowed the investigation�…