Context: Observations in rodents suggest that osteocalcin (OC) participates in glucose
metabolism. Based on human studies, it remains unclear whether circulating OC is simply a�…

Context: It has been assumed that the increase in urine calcium (Ca) that accompanies an
increase in dietary protein was due to increased bone resorption. However, studies using�…

Microgravity induces significant and progressive bone loss in both humans and animals.
This is the consequence of disturbed bone remodeling. We performed a bed rest experiment�…

Bone is permanently remodeled by a complex network of local, hormonal, and neuronal
factors that affect osteoclast and osteoblast biology. Among these factors, a role for�…

Glucose-dependent insulinotropic peptide (GIP) is an intestinally secreted hormone the
release of which is stimulated by nutrient ingestion. We previously reported that GIP�…

It is unclear whether both bone resorption and formation are affected by glycemic control,
and contribute to diabetic osteopenia. In this study, 20 patients with noninsulin-dependent�…

A new immunoassay using an ELISA approach for measuring urinary excretion of cross‐
linked N‐telopeptides of type 1 collagen was evaluated as a specific measure of bone�…

Objective To determine whether dietary counseling to increase milk intake could produce
useful changes in the calcium economy and what, if any, other nutrition-related changes�…

Advanced glycation endproducts (AGEs) are chemical modifications of proteins by
carbohydrates including those metabolic intermediates formed during the Maillard reaction�…

Severe chronic undernutrition is associated with decreased bone turnover and significant
bone loss. However, little is known about the short-term effects of nutritional deprivation on�…