[HTML][HTML] A narrative review of the effects of citrus peels and extracts on human brain health and metabolism

K Matsuzaki, A Nakajima, Y Guo, Y Ohizumi�- Nutrients, 2022 - mdpi.com
As life expectancy increases, age-associated diseases such as Alzheimer's disease (AD)
become a major health problem. The onset of AD involves neurological dysfunction due to�…

Citrus flavonoids and effects in dementia and age-related cognitive decline

SL Hwang, PH Shih, GC Yen�- Diet and nutrition in dementia and cognitive�…, 2015 - Elsevier
The influence of dietary and citrus flavonoids on health and mental well-being has been
increasingly attractive. They exert antioxidative, antiinflammatory, and neuroprotective�…

[HTML][HTML] Citrus polyphenols in brain health and disease: current perspectives

MG Pontifex, MMAH Malik, E Connell…�- Frontiers in�…, 2021 - frontiersin.org
In addition to essential micronutrients such as vitamin C, citrus fruits represent a
considerably rich source of non-essential bioactive compounds, in particular flavanones�…

[HTML][HTML] Cognitive and biological effects of citrus phytochemicals in subjective cognitive decline: a 36-week, randomized, placebo-controlled trial

S Galluzzi, R Zanardini, C Ferrari, S Gipponi…�- Nutrition Journal, 2022 - Springer
Background Auraptene (AUR) and naringenin (NAR) are citrus-derived phytochemicals that
influence several biological mechanisms associated with cognitive decline, including�…

Neuroprotective effects of citrus flavonoids

SL Hwang, PH Shih, GC Yen�- Journal of Agricultural and Food�…, 2012 - ACS Publications
Recent attention has been given to the influence of dietary factors on health and mental well-
being. Oxidative stress is associated with many diseases including neurodegenerative�…

[HTML][HTML] Beneficial effects of citrus-derived polymethoxylated flavones for central nervous system disorders

K Matsuzaki, Y Ohizumi�- Nutrients, 2021 - mdpi.com
The number of patients with central nervous system disorders is increasing. Despite diligent
laboratory and clinical research over the past 30 years, most pharmacologic options for the�…

Citrus fruit polyphenols and flavonoids: Applications to psychiatric disorders

MRA Muscatello, RA Zoccali, A Bruno�- …�of action in human health and�…, 2018 - Elsevier
A significant amount of evidence suggests that oxidative stress and activated immune and
inflammatory pathways are involved not only in normal aging and in neurodegenerative�…

[HTML][HTML] Neurodegenerative Diseases: Might Citrus Flavonoids Play a Protective Role?

S Cirmi, N Ferlazzo, GE Lombardo…�- Molecules, 2016 - mdpi.com
Neurodegenerative diseases (ND) result from the gradual and progressive degeneration of
the structure and function of the central nervous system or the peripheral nervous system or�…

[HTML][HTML] Effect of polyphenols on cognitive function: evidence from population-based studies and clinical trials

W Yang, K Cui, X Li, J Zhao, Z Zeng, R Song…�- The Journal of nutrition�…, 2021 - Elsevier
Due to progressive population aging, a new dementia case occurs at every 3 seconds,
placing a heavy burden of disease. Identifying potential risk or preventive factors is�…

Metabolic and immune risk factors for dementia and their modification by flavonoids: New targets for the prevention of cognitive impairment?

C Saunders, JPE Spencer�- Nutrition and Aging, 2012 - content.iospress.com
A number of contributory factors have been implicated in the pathogenesis of Alzheimer's
disease. One of these factors is chronic inflammation, with the over expression of pro�…