[HTML][HTML] Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies
SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and
can be followed by low-level persistent viral RNA shedding. The dynamics of viral RNA�…
can be followed by low-level persistent viral RNA shedding. The dynamics of viral RNA�…
Clinical performance of SARS-CoV-2 molecular tests
Molecular testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
gold standard for diagnosis of coronavirus disease 2019 (COVID-19), but the clinical�…
gold standard for diagnosis of coronavirus disease 2019 (COVID-19), but the clinical�…
Longitudinal assessment of diagnostic test performance over the course of acute SARS-CoV-2 infection
Background Serial screening is critical for restricting spread of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) by facilitating timely identification of infected�…
syndrome coronavirus 2 (SARS-CoV-2) by facilitating timely identification of infected�…
[HTML][HTML] Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections
J Hellewell, TW Russell, R Beale, G Kelly, C Houlihan…�- BMC medicine, 2021 - Springer
Background Routine asymptomatic testing using RT-PCR of people who interact with
vulnerable populations, such as medical staff in hospitals or care workers in care homes�…
vulnerable populations, such as medical staff in hospitals or care workers in care homes�…
Can testing predict SARS-CoV-2 infectivity? The potential for certain methods to be surrogates for replication-competent virus
MJ Binnicker�- Journal of clinical microbiology, 2021 - Am Soc Microbiol
Since the beginning of the COVID-19 pandemic, molecular methods (eg, real-time PCR)
have been the primary means of diagnosing the disease. It is now well established that�…
have been the primary means of diagnosing the disease. It is now well established that�…
Estimating infectiousness throughout SARS-CoV-2 infection course
INTRODUCTION Although post facto studies have revealed the importance of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic�…
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic�…
Direct comparison of SARS-CoV-2 analytical limits of detection across seven molecular assays
B Fung, A Gopez, V Servellita, S Arevalo…�- Journal of clinical�…, 2020 - Am Soc Microbiol
Analytical sensitivity for SARS-CoV-2 detection is a key performance metric for the
evaluation of viral detection assays. We determined analytical limits of detection for seven�…
evaluation of viral detection assays. We determined analytical limits of detection for seven�…
Epidemiological correlates of polymerase chain reaction cycle threshold values in the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Background Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection has principally been performed through the use of real-time reverse-transcription�…
infection has principally been performed through the use of real-time reverse-transcription�…
Validation and verification of the Abbott RealTime SARS-CoV-2 assay analytical and clinical performance
E Degli-Angeli, J Dragavon, ML Huang, D Lucic…�- Journal of Clinical�…, 2020 - Elsevier
Background High-throughput assays for the SARS-CoV-2 virus are critical to increasing test
capacity and slowing the spread of COVID-19. Abbott Molecular developed and received�…
capacity and slowing the spread of COVID-19. Abbott Molecular developed and received�…
Quantitative SARS-CoV-2 viral-load curves in paired saliva samples and nasal swabs inform appropriate respiratory sampling site and analytical test sensitivity�…
ES Savela, A Viloria Winnett, AE Romano…�- Journal of clinical�…, 2022 - Am Soc Microbiol
Early detection of SARS-CoV-2 infection is critical to reduce asymptomatic and
presymptomatic transmission, curb the spread of variants, and maximize treatment efficacy�…
presymptomatic transmission, curb the spread of variants, and maximize treatment efficacy�…
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