Gestational diabetes mellitus (GDM) is a serious pregnancy complication, in which women
without previously diagnosed diabetes develop chronic hyperglycemia during gestation. In�…

Throughout its entire lifespan, the placenta is able to produce as well as respond to a variety
of inflammatory stimuli. Many signaling molecules and concurrent pathways responsible for�…

Adverse influences during fetal life alter the structure and function of distinct cells, organ
systems or homoeostatic pathways, thereby 'programming'the individual for an increased�…

Diabetes mellitus (DM) during pregnancy can result in fetal overgrowth, likely due to
placental dysfunction, which has health consequences for the infant. Here we test our�…

Gestational diabetes mellitus (GDM) is an obstetric complication that affects approximately 5–
10% of all pregnancies worldwide. GDM is defined as any degree of glucose intolerance�…

Hormones have an important role in regulating fetal development. They act as
environmental signals and integrate tissue growth and differentiation with relation to nutrient�…

Maternal obesity during pregnancy is rising and is associated with increased risk of
developing gestational diabetes mellitus (GDM), defined as glucose intolerance first�…

The placenta is a unique, autonomous and transient organ. It ensures maternal–fetal
exchanges and is also involved in maternal tolerance of feto-paternal antigens. The human�…

Gestational diabetes mellitus (GDM) is a metabolic disorder prevalent among pregnant
women. This disease increases the risk of adverse perinatal outcomes and diseases in the�…

Introduction Maternal nutritional and metabolic factors influence the developmental
environment of the fetus. Virtually any nutritional factor in the maternal blood has to pass the�…