The purpose of the present study was to investigate the mechanisms by which estrogen
production arises in the human female following the menopause. The possibilities�…

The purpose of the present study was to ascertain the relationship between aging and the
extent of conversion of plasma androstenedione to estrone. Studies were carried out in 23�…

In postmenopausal women, the circulating levels of estrone (E 1) and estradiol (E 2) may be
of clinical importance. The origin of E 1, but not of E 2, has been defined. To examine the�…

After the intravenous administration of tracer doses of 4-14C-Δ4-androstenedione+ 6, 7-3H-
estrone (or 6, 7-3H-estradiol) to normal adult males, and normal, castrate and�…

Urinary production rates of dehydroepiandrosterone (D) and dehydroepiandrosterone
sulfate (DS) by isotope dilution, and the blood production rate of androstenedione (A) by�…

Plasma sex hormone concentrations (testosterone,(T), androstenedione (A), oestrone (E1)
and oestradiol (E2) were measured in forty post-menopausal women more than 4 years post�…

Continuous infusions of Δ4-androstenedione-7-3H and testosterone-7-3H have been used
to demonstrate that these androgens are converted to estrone and 17β-estradiol, and�…

Previous studies from this laboratory have included reports on the serum concentrations of
the following steroids in premenopausal and postmenopausal women: pregnenolone, 17�…

The origin of plasma sex hormones in postmenopausal women was studied by determining
plasma levels under basal conditions, after ACTH stimulation, and after dexamethasone�…

T HE simultaneous occurrence of two or more estrogens within the same animal has been a
frequent topic for conjectural discussions as to possible physiologic and biochemical�…