Adaptive immune components are thought to exert non-overlapping roles in antimicrobial
host defence, with antibodies targeting pathogens in the extracellular environment and T�…

Although maternal antibodies protect newborn babies from infection,, little is known about
how protective antibodies are induced without prior pathogen exposure. Here we show that�…

Innate immunity: The unsung heroes | Nature Skip to main content Thank you for visiting
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Discrimination of self from non-self is fundamental to a wide range of immunological
processes. During pregnancy, the mother does not recognize the placenta as�…

Newborn infants are highly susceptible to infection. This defect in host defence has
generally been ascribed to the immaturity of neonatal immune cells; however, the degree of�…

Systemic infection with Listeria monocytogenes, a Gram-positive intracellular bacterium, has
been used extensively to analyze the innate immune response 1, 2. Macrophages are�…

As the first line of defence against pathogens, cells mount an innate immune response,
which varies widely from cell to cell. The response must be potent but carefully controlled to�…

The innate immune response--an inflammatory reaction that helps control infections in their
early stages--has long been the Cinderella of immunology. For decades, innate immunity�…

The innate and adaptive immune systems act in concert to effectively combat infection while
minimizing collater al damage caused by the host immune response. T cells of the adaptive�…

Neonates face a high risk of infection because of the immaturity of their immune systems.
Although the transplacental transfer of maternal antibodies to the fetus may convey�…