In vitro and in vivo studies have identified the pre-B�tzinger complex as an important kernel
for the generation of inspiratory activity. The mechanisms underlying inspiratory rhythm�…

Breathing is controlled by a distributed network involving areas in the neocortex, cerebellum,
pons, medulla, spinal cord, and various other subcortical regions. However, only one area�…

PreB�tzinger Complex (preB�tC) neurons are postulated to underlie respiratory rhythm
generation. The inspiratory phase of the respiratory cycle in vitro results from preB�tC�…

Breathing in mammals is a seemingly straightforward behaviour controlled by the brain. A
brainstem nucleus called the preB�tzinger Complex sits at the core of the neural circuit�…

Neurons within the preB�tzinger complex (pBc) are postulated to have a central role in
respiratory rhythm generation. This postulate is supported by studies using both in vitro and�…

We used the testable predictions of mathematical models proposed by Butera et al. to
evaluate cellular, synaptic, and population-level components of the hypothesis that�…

The preB�tzinger Complex (preB�tC), a medullary network critical for breathing, relies on
excitatory interneurons to generate the inspiratory rhythm. Yet, half of preB�tC neurons are�…

▪ Abstract Identification of the sites and mechanisms underlying the generation of respiratory
rhythm is of longstanding interest to physiologists and neurobiologists. Recently, with the�…

The generation of neural network dynamics relies on the interactions between the intrinsic
and synaptic properties of their neural components. Moreover, neuromodulators allow�…

Shao, Xuesi M. and Jack L. Feldman. Respiratory rhythm generation and synaptic inhibition
of expiratory neurons in pre-Bötzinger complex: differential roles of glycinergic and�…