Ischemia reperfusion injury results from tissue damage during ischemia and ongoing
inflammation and injury during reperfusion. Liver reperfusion injury is reduced by�…

Ischemia-reperfusion (I/R) injury occurs as a result of restoring blood flow to previously
hypoperfused vessels or after tissue transplantation and is characterized by inflammation�…

Abstract A 2A adenosine receptor (A 2A R)-expressing bone marrow (BM)-derived cells
contribute to the renal protective effect of A 2A agonists in renal ischemia-reperfusion injury�…

Activation of the A 2A adenosine receptor (A 2A R) during reperfusion of various tissues has
been found to markedly reduce ischemia-reperfusion injury. In this study, we used bone�…

To examine whether adenosine reduces ischemia/reperfusion (I/R)-induced liver injury by
inhibiting leukocyte activation via A2receptor (A2R) stimulation, we investigated the effects�…

Background—We previously used adenosine A2A receptor (A2AR) knockout (KO) mice and
bone marrow transplantation to show that the infarct-sparing effect of A2AR activation at�…

Natural killer (NK) cells play crucial roles in innate immunity and express CD39 (Ecto‐
nucleoside triphosphate diphosphohydrolase 1 [E‐NTPD1]), a rate‐limiting�…

Gastrointestinal ischemia/reperfusion (IR) injury significantly contributes to the morbidity and
mortality of critical illness. In this study, we hypothesized a protective role for extracellular�…

BACKGROUND & AIMS:: Hepatic ischemic reperfusion injury (IRI) is a major complication of
liver transplantation and resectional hepatic surgeries. Natural killer T (NKT) cells�…

Background—A2A-adenosine receptor (A2AAR) activation on reperfusion after ischemia
reduces the size of myocardial infarction, but the mechanism of action has not been fully�…