A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain�…

HY Shen, JE Coelho, N Ohtsuka…�- Journal of�…, 2008 - Soc Neuroscience
The function of striatal adenosine A 2A receptors (A 2A Rs) is well recognized because of
their high expression levels and the documented antagonistic interaction between A 2A Rs�…

Selective attenuation of psychostimulant-induced behavioral responses in mice lacking A2A adenosine receptors

JF Chen, M Beilstein, YH Xu, TJ Turner, R Moratalla…�- Neuroscience, 2000 - Elsevier
A2A adenosine receptors are highly expressed in the striatum where they modulate
dopaminergic activity. The role of A2A receptors in psychostimulant action is less well�…

[HTML][HTML] Adenosine A2A Receptors and A2A Receptor Heteromers as Key Players in Striatal Function

S Ferr�, C Quiroz, M Orru, X Guitart…�- Frontiers in�…, 2011 - frontiersin.org
A very significant density of adenosine A2A receptors (A2ARs) is present in the striatum,
where they are preferentially localized postsynaptically in striatopallidal medium spiny�…

Anatomy of adenosine A2A receptors in brain: Morphological substrates for integration of striatal function

DL Rosin, BD Hettinger, A Lee, J Linden�- Neurology, 2003 - AAN Enterprises
A2A adenosine receptors (A2ARs) are expressed with the greatest abundance in the
striatum and other nuclei of the basal ganglia. The segregated expression of A2ARs on the�…

[HTML][HTML] A crucial role for forebrain adenosine A2A receptors in amphetamine sensitization

E Bastia, YH Xu, AC Scibelli, YJ Day, J Linden…�- …, 2005 - nature.com
Abstract Adenosine A 2A receptors (A 2A Rs) are well positioned to influence the
maladaptive CNS responses to repeated dopaminergic stimulation in psychostimulant�…

Adenosine A2A receptors in psychopharmacology: modulators of behavior, mood and cognition

HY Shen, JF Chen�- Current neuropharmacology, 2009 - ingentaconnect.com
The adenosine A2A receptor (A2AR) is in the center of a neuromodulatory network affecting
a wide range of neuropsychiatric functions by interacting with and integrating several�…

Are A3 adenosine receptors expressed in the brain?

SA Rivkees, S Thevananther, H Hao�- Neuroreport, 2000 - journals.lww.com
An increasing number of reports suggest a role for A3 adenosine receptors (A3ARs) in
mediating adenosine action in the central nervous system. However, studies of A3AR�…

Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry: implications for drug addiction, sleep and pain

S Ferr�, I Diamond, SR Goldberg, L Yao…�- Progress in�…, 2007 - Elsevier
Adenosine A2A receptors localized in the dorsal striatum are considered as a new target for
the development of antiparkinsonian drugs. Co-administration of A2A receptor antagonists�…

[HTML][HTML] Adenosine A2A Receptors in Striatal Glutamatergic Terminals and GABAergic Neurons Oppositely Modulate Psychostimulant Action and DARPP-32�…

HY Shen, PM Canas, P Garcia-Sanz, JQ Lan…�- PLoS�…, 2013 - journals.plos.org
Adenosine A2A receptors (A2AR) are located postsynaptically in striatopallidal GABAergic
neurons, antagonizing dopamine D2 receptor functions, and are also located�…

Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons

SN Schiffmann, JJ Vanderhaeghen�- Journal of Neuroscience, 1993 - Soc Neuroscience
Adenosine acts as a neuromodulator through A1 and A2 receptors. The adenosine analogs
have been recognized, among other effects, as strong depressors of the locomotor activity�…