A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain�…
HY Shen, JE Coelho, N Ohtsuka…�- Journal of�…, 2008 - Soc Neuroscience
The function of striatal adenosine A 2A receptors (A 2A Rs) is well recognized because of
their high expression levels and the documented antagonistic interaction between A 2A Rs�…
their high expression levels and the documented antagonistic interaction between A 2A Rs�…
Selective attenuation of psychostimulant-induced behavioral responses in mice lacking A2A adenosine receptors
JF Chen, M Beilstein, YH Xu, TJ Turner, R Moratalla…�- Neuroscience, 2000 - Elsevier
A2A adenosine receptors are highly expressed in the striatum where they modulate
dopaminergic activity. The role of A2A receptors in psychostimulant action is less well�…
dopaminergic activity. The role of A2A receptors in psychostimulant action is less well�…
[HTML][HTML] Adenosine A2A Receptors and A2A Receptor Heteromers as Key Players in Striatal Function
S Ferr�, C Quiroz, M Orru, X Guitart…�- Frontiers in�…, 2011 - frontiersin.org
A very significant density of adenosine A2A receptors (A2ARs) is present in the striatum,
where they are preferentially localized postsynaptically in striatopallidal medium spiny�…
where they are preferentially localized postsynaptically in striatopallidal medium spiny�…
Anatomy of adenosine A2A receptors in brain: Morphological substrates for integration of striatal function
A2A adenosine receptors (A2ARs) are expressed with the greatest abundance in the
striatum and other nuclei of the basal ganglia. The segregated expression of A2ARs on the�…
striatum and other nuclei of the basal ganglia. The segregated expression of A2ARs on the�…
[HTML][HTML] A crucial role for forebrain adenosine A2A receptors in amphetamine sensitization
E Bastia, YH Xu, AC Scibelli, YJ Day, J Linden…�- …, 2005 - nature.com
Abstract Adenosine A 2A receptors (A 2A Rs) are well positioned to influence the
maladaptive CNS responses to repeated dopaminergic stimulation in psychostimulant�…
maladaptive CNS responses to repeated dopaminergic stimulation in psychostimulant�…
Adenosine A2A receptors in psychopharmacology: modulators of behavior, mood and cognition
HY Shen, JF Chen�- Current neuropharmacology, 2009 - ingentaconnect.com
The adenosine A2A receptor (A2AR) is in the center of a neuromodulatory network affecting
a wide range of neuropsychiatric functions by interacting with and integrating several�…
a wide range of neuropsychiatric functions by interacting with and integrating several�…
Are A3 adenosine receptors expressed in the brain?
SA Rivkees, S Thevananther, H Hao�- Neuroreport, 2000 - journals.lww.com
An increasing number of reports suggest a role for A3 adenosine receptors (A3ARs) in
mediating adenosine action in the central nervous system. However, studies of A3AR�…
mediating adenosine action in the central nervous system. However, studies of A3AR�…
Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry: implications for drug addiction, sleep and pain
S Ferr�, I Diamond, SR Goldberg, L Yao…�- Progress in�…, 2007 - Elsevier
Adenosine A2A receptors localized in the dorsal striatum are considered as a new target for
the development of antiparkinsonian drugs. Co-administration of A2A receptor antagonists�…
the development of antiparkinsonian drugs. Co-administration of A2A receptor antagonists�…
[HTML][HTML] Adenosine A2A Receptors in Striatal Glutamatergic Terminals and GABAergic Neurons Oppositely Modulate Psychostimulant Action and DARPP-32�…
HY Shen, PM Canas, P Garcia-Sanz, JQ Lan…�- PLoS�…, 2013 - journals.plos.org
Adenosine A2A receptors (A2AR) are located postsynaptically in striatopallidal GABAergic
neurons, antagonizing dopamine D2 receptor functions, and are also located�…
neurons, antagonizing dopamine D2 receptor functions, and are also located�…
Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons
SN Schiffmann, JJ Vanderhaeghen�- Journal of Neuroscience, 1993 - Soc Neuroscience
Adenosine acts as a neuromodulator through A1 and A2 receptors. The adenosine analogs
have been recognized, among other effects, as strong depressors of the locomotor activity�…
have been recognized, among other effects, as strong depressors of the locomotor activity�…