Langerhans cells (LC) have recently been shown to be the only epidermal cells that bear Fc
and C3 receptors, and that express Ia antigens on their surface, supporting the hypothesis�…

Epidermal Langerhans cells have been implicated in the process by which animals skin
painted with highly reactive haptens, such as DNFB, develop contact hypersensitivity�…

Langerhans-cell-enriched epidermal cell preparations, when pulsed with antigen, can
induce proliferative responses, in immune T cells, that are of the same magnitude as those�…

The presence of Langerhans cells (LC) within the epidermis has been shown to be critical
for inducing T-cell-mediated immune responses in the skin. The purpose of this study was to�…

Summary Epidermal Langerhans cells (LCs), a distinct skin-resident dendritic cell
population, acquire antigen in the skin and migrate to draining lymph nodes where they are�…

Langerhans cells (LC) constitute a morphologically well-characterized minor subpopulation
of the mammalian epidermis whose functional role is still a matter of conjecture. The�…

One explanation for the fact that certain genetically defined strains of mice prove to be
resistant to effects of low dose ultraviolet B radiation on the induction of contact�…

Our assumptions on the identity and functions of Langerhans cells (LCs) of the epidermis
have undergone considerable changes. Once thought to be prototypic representatives of the�…

In the past few years there has been an explosion in the characterization of skin-resident
dendritic cells (DCs). This is largely because of the development of several lines of mice with�…

Langerhans cells and other skin-resident dendritic cells (DC) are required for the
development of cutaneous adaptive immune responses. In vivo experiments using mice with�…