Butyrate-producing human gut symbiont, Clostridium butyricum, and its role in health and disease

MK Stoeva, J Garcia-So, N Justice, J Myers, S Tyagi…�- Gut�…, 2021 - Taylor & Francis
Clostridium butyricum is a butyrate-producing human gut symbiont that has been safely
used as a probiotic for decades. C. butyricum strains have been investigated for potential�…

Butyrate Producers as Potential Next-Generation Probiotics: Safety Assessment of the Administration of Butyricicoccus pullicaecorum to Healthy Volunteers

L Boesmans, M Valles-Colomer, J Wang, V Eeckhaut…�- Msystems, 2018 - Am Soc Microbiol
Advances in gut microbiota research have triggered interest in developing colon butyrate
producers as niche-specific next-generation probiotics, targeted at increasing colon butyrate�…

[HTML][HTML] Effect of Clostridium butyricum on Gastrointestinal Infections

T Ariyoshi, M Hagihara, M Takahashi, H Mikamo�- Biomedicines, 2022 - mdpi.com
Clostridium butyricum is a human commensal bacterium with beneficial effects including
butyrate production, spore formation, increasing levels of beneficial bacteria, and inhibition�…

[HTML][HTML] Butyrate-producing bacteria supplemented in vitro to Crohn's disease patient microbiota increased butyrate production and enhanced intestinal epithelial�…

A Geirnaert, M Calatayud, C Grootaert, D Laukens…�- Scientific reports, 2017 - nature.com
The management of the dysbiosed gut microbiota in inflammatory bowel diseases (IBD) is
gaining more attention as a novel target to control this disease. Probiotic treatment with�…

[HTML][HTML] Prospects for clinical applications of butyrate-producing bacteria

LB Zhu, YC Zhang, HH Huang, J Lin�- World journal of clinical�…, 2021 - ncbi.nlm.nih.gov
As the major source of energy for colonic mucosal cells and as an important regulator of
gene expression, inflammation, differentiation, and apoptosis in host cells, microbiota�…

[HTML][HTML] Butyrate producers,“The Sentinel of Gut”: Their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics

V Singh, GD Lee, HW Son, H Koh, ES Kim…�- Frontiers in�…, 2023 - frontiersin.org
Gut-microbial butyrate is a short-chain fatty acid (SCFA) of significant physiological
importance than the other major SCFAs (acetate and propionate). Most butyrate producers�…

Butyrate supplementation at high concentrations alters enteric bacterial communities and reduces intestinal inflammation in mice infected with Citrobacter rodentium

JA Jiminez, TC Uwiera, DW Abbott, RRE Uwiera…�- MSphere, 2017 - Am Soc Microbiol
Butyrate is a short-chain fatty acid by-product of the microbial fermentation of dietary
fermentable materials in the large intestine; it is the main energy source for enterocyte�…

Butyricicoccus pullicaecorum, a butyrate producer with probiotic potential, is intrinsically tolerant to stomach and small intestine conditions

A Geirnaert, A Steyaert, V Eeckhaut, B Debruyne…�- Anaerobe, 2014 - Elsevier
Butyrate has several beneficial properties that are essential to maintain gastrointestinal
health. Therefore butyrate-producing bacteria are seen as the next generation of probiotics�…

Clostridium butyricum and its derived extracellular vesicles modulate gut homeostasis and ameliorate acute experimental colitis

L Ma, Q Shen, W Lyu, L Lv, W Wang, M Yu…�- Microbiology�…, 2022 - Am Soc Microbiol
Microbiological treatments are expected to have a role in the future management of
inflammatory bowel disease (IBD). Clostridium butyricum (C. butyricum) is a probiotic�…

[HTML][HTML] Clostridium Butyricum CGMCC0313.1 Modulates Lipid Profile, Insulin Resistance and Colon Homeostasis in Obese Mice

H Shang, J Sun, YQ Chen�- PloS one, 2016 - journals.plos.org
Obesity is associated with a cluster of metabolic disorders and systemic low-grade
inflammation involving multiple organs. Recent findings have suggested that intestine is a�…