[HTML][HTML] Immunoendocrine dysregulation during gestational diabetes mellitus: The central role of the placenta

A Olmos-Ortiz, P Flores-Espinosa, L D�az…�- International Journal of�…, 2021 - mdpi.com
Gestational Diabetes Mellitus (GDM) is a transitory metabolic condition caused by
dysregulation triggered by intolerance to carbohydrates, dysfunction of beta-pancreatic and�…

[HTML][HTML] Gestational diabetes mellitus and maternal immune dysregulation: what we know so far

CJ McElwain, FP McCarthy, CM McCarthy�- International Journal of�…, 2021 - mdpi.com
Gestational diabetes mellitus (GDM) is an obstetric complication that affects approximately 5–
10% of all pregnancies worldwide. GDM is defined as any degree of glucose intolerance�…

[HTML][HTML] Placental endocrine activity: adaptation and disruption of maternal glucose metabolism in pregnancy and the influence of fetal sex

C Stern, S Schwarz, G Moser, S Cvitic…�- International journal of�…, 2021 - mdpi.com
The placenta is an endocrine fetal organ, which secretes a plethora of steroid-and proteo-
hormones, metabolic proteins, growth factors, and cytokines in order to adapt maternal�…

[HTML][HTML] Maternal β-cell adaptations in pregnancy and placental signalling: implications for gestational diabetes

BL Moyce, VW Dolinsky�- International journal of molecular sciences, 2018 - mdpi.com
Rates of gestational diabetes mellitus (GDM) are on the rise worldwide, and the number of
pregnancies impacted by GDM and resulting complications are also increasing. Pregnancy�…

Impact of systemic inflammation on the progression of gestational diabetes mellitus

T Lekva, ER Norwitz, P Aukrust, T Ueland�- Current diabetes reports, 2016 - Springer
With increasing rates of obesity and new diagnostic criteria for gestational diabetes mellitus
(GDM), the overall prevalence of GDM is increasing worldwide. Women with GDM have an�…

[HTML][HTML] Molecular pathways disrupted by gestational diabetes mellitus

C Nguyen-Ngo, N Jayabalan…�- Journal of molecular�…, 2019 - jme.bioscientifica.com
Gestational diabetes mellitus (GDM) imposes serious short-and long-term health problems
for mother and baby. An effective therapeutic that can reduce the incidence of GDM and�…

An interplay between obesity and inflammation in gestational diabetes mellitus

E Sk�rzyŦ, Ż Kimber-Trojnar…�- Current�…, 2016 - ingentaconnect.com
Gestational diabetes mellitus (GDM) is traditionally defined as hyperglycemia first detected
in pregnancy. The risk of GDM is much higher among obese women than in their lean�…

Altered cytokine network in gestational diabetes mellitus affects maternal insulin and placental–fetal development

L Wedekind, L Belkacemi�- Journal of Diabetes and its Complications, 2016 - Elsevier
Pregnancy is characterized by an altered inflammatory profile, compared to the non-
pregnant state with an adequate balance between pro-and anti-inflammatory cytokines�…

Gestational diabetes induces placental genes for chronic stress and inflammatory pathways

T Radaelli, A Varastehpour, P Catalano…�- Diabetes, 2003 - Am Diabetes Assoc
A physiological state of insulin resistance is required to preferentially direct maternal
nutrients toward the feto-placental unit, allowing adequate growth of the fetus. When women�…

[HTML][HTML] Inflammatory and other biomarkers: role in pathophysiology and prediction of gestational diabetes mellitus

SK Abell, B De Courten, JA Boyle…�- International journal of�…, 2015 - mdpi.com
Understanding pathophysiology and identifying mothers at risk of major pregnancy
complications is vital to effective prevention and optimal management. However, in current�…