[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–Current perspectives

JL Boechat, I Chora, A Morais, L Delgado�- Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID�…

Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview

LM Khosroshahi, M Rokni, T Mokhtari…�- International�…, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) infection which is caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a “public health emergency of�…

[HTML][HTML] Recent insight into SARS-CoV2 immunopathology and rationale for potential treatment and preventive strategies in COVID-19

S Lega, S Naviglio, S Volpi, A Tommasini�- Vaccines, 2020 - mdpi.com
As the outbreak of the new coronavirus (SARS-CoV-2) infection is spreading globally, great
effort is being made to understand the disease pathogenesis and host factors that�…

COVID-19: Immunology and treatment options

S Felsenstein, JA Herbert, PS McNamara…�- Clinical�…, 2020 - Elsevier
The novel coronavirus SARS-CoV2 causes COVID-19, a pandemic threatening millions. As
protective immunity does not exist in humans and the virus is capable of escaping innate�…

[HTML][HTML] Innate immunity in protection and pathogenesis during coronavirus infections and COVID-19

RKS Malireddi, BR Sharma…�- Annual Review of�…, 2024 - annualreviews.org
The COVID-19 pandemic was caused by the recently emerged β-coronavirus SARS-CoV-2.
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide�…

[HTML][HTML] Unraveling the mystery surrounding post-acute sequelae of COVID-19

RK Ramakrishnan, T Kashour, Q Hamid…�- Frontiers in�…, 2021 - frontiersin.org
More than one year since its emergence, corona virus disease 2019 (COVID-19) is still
looming large with a paucity of treatment options. To add to this burden, a sizeable subset of�…

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan…�- Signal transduction and�…, 2020 - nature.com
The recent novel coronavirus disease (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is seeing a rapid increase in infected�…

[HTML][HTML] Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC)

S Mohandas, P Jagannathan, TJ Henrich, ZA Sherif…�- Elife, 2023 - elifesciences.org
With a global tally of more than 500 million cases of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections to date, there are growing concerns about the post�…

[HTML][HTML] SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”

BL Sievers, MTK Cheng, K Csiba, B Meng…�- Cellular & Molecular�…, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological�…

[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini…�- Signal transduction and�…, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast�…