After briefly discussing human exposure to phthalates—diesters of 1, 2-benzenedicarboxylic
acid (phthalic acid)—this article first presents recent findings from the Study for Future�…

Adverse birth outcomes present risk factors resulting in neonatal morbidity and mortality.
Sufficient maternal hormonal concentrations are crucial for normal foetal development�…

Background Phthalates may pose a risk for perinatal developmental effects. An important
question relates to the choice of suitable biological matrices for assessing exposure during�…

Higher concentrations of certain phthalate metabolites are associated with adverse
reproductive and pregnancy outcomes, as well as poor infant/child health outcomes. In non�…

Emerging evidence from observational studies proves the association between preterm birth
(PTB) and phthalate metabolites; however, such findings are inconsistent and inconclusive�…

Phthalates, widely used as plasticizers, are contained in many everyday products. Human
biomonitoring studies detect their presence in biological fluids of a large part of the�…

Background Phthalates have been linked with numerous harmful health effects. Limited data
are available on the molecular mechanism underlying phthalate toxicity on human health. In�…

Objective To study associations between prenatal exposure to phthalates and fetal and
postnatal growth up to age 5 years in male offspring. Methods Eleven phthalate metabolites�…

Background Some phthalate chemicals can affect hormone physiology in utero resulting in
adverse reproductive health outcomes in animal models. It is unknown whether these�…

Prenatal phthalate exposure has been shown to be associated with reduced fetal growth.
Epigenetic changes such as DNA methylation might be a molecular mechanism through�…