Preconception Phthalate Exposure and Women's Reproductive Health: Pregnancy, Pregnancy Loss, and Underlying Mechanisms

CJ Nobles, P Mendola, K Kim, AZ Pollack…�- Environmental�…, 2023 - ehp.niehs.nih.gov
Background: Phthalates are endocrine-disrupting chemicals linked to adverse pregnancy
outcomes. Despite the sensitivity of female reproductive processes to oxidation–reduction�…

Prenatal phenol and phthalate exposures and birth outcomes

MS Wolff, SM Engel, GS Berkowitz, X Ye…�- Environmental�…, 2008 - ehp.niehs.nih.gov
Background Many phthalates and phenols are hormonally active and are suspected to alter
the course of development. Objective We investigated prenatal exposures to phthalate and�…

Sex-specific difference in placental inflammatory transcriptional biomarkers of maternal phthalate exposure: a prospective cohort study

JQ Wang, YB Hu, H Gao, J Sheng, K Huang…�- Journal of Exposure�…, 2020 - nature.com
Previous epidemiologic research has shown that phthalate exposure in pregnant women is
related to birth outcomes in a sex-specific manner. These outcomes may be mediated by�…

Urinary phthalate metabolites in relation to preterm birth in Mexico city

JD Meeker, H Hu, DE Cantonwine…�- Environmental�…, 2009 - ehp.niehs.nih.gov
Background Rates of preterm birth have been rising over the past several decades. Factors
contributing to this trend remain largely unclear, and exposure to environmental�…

Placental outcomes of phthalate exposure

GR Warner, RS Dettogni, IC Bagchi, JA Flaws…�- Reproductive�…, 2021 - Elsevier
Proper placental development and function relies on hormone receptors and signaling
pathways that make the placenta susceptible to disruption by endocrine disrupting�…

[HTML][HTML] Maternal urinary phthalates and sex-specific placental mRNA levels in an urban birth cohort

JJ Adibi, JP Buckley, MK Lee, PL Williams, AC Just…�- Environmental�…, 2017 - Springer
Background Prenatal urinary concentrations of phthalates in women participants in an urban
birth cohort were associated with outcomes in their children related to neurodevelopment�…

[HTML][HTML] Phthalate exposure and female reproductive and developmental outcomes: a systematic review of the human epidemiological evidence

EG Radke, BS Glenn, JM Braun, GS Cooper�- Environment international, 2019 - Elsevier
Objective We performed a systematic review of the epidemiology literature to identify the
female reproductive and developmental effects associated with phthalate exposure. Data�…

Prenatal exposure to a mixture of different phthalates increases the risk of mammary carcinogenesis in F1 female offspring

T de Freitas, JR Zapaterini, CM Moreira…�- Food and Chemical�…, 2021 - Elsevier
Phthalates metabolites have been detected in the urine of pregnant and breastfeeding
women. Thus, this study evaluated the adverse effects of maternal exposure to a mixture of�…

Fetal exposure to phthalates–a pilot study

M Wittassek, J Angerer, M Kolossa-Gehring…�- International journal of�…, 2009 - Elsevier
The fetus is considered to be the most sensitive stage of life to the potential developmental
and reproductive toxicity of the phthalates. But, data on human fetal exposure to phthalates�…

Prenatal phthalate exposure and placental size and shape at birth: a birth cohort study

Y Zhu, H Gao, K Huang, Y Zhang, X Cai, H Yao…�- Environmental�…, 2018 - Elsevier
Objective There is concern over the potential placental effects of prenatal phthalate
exposure, and the potential adverse effects of prenatal phthalate exposure require further�…