Background Sepsis is life-threatening organ dysfunction due to a dysregulated host
response to infection. It is considered a major cause of health loss, but data for the global�…

Background Improved understanding of pathogens that cause sepsis would aid
management and antimicrobial selection. In this study, we aimed to identify the causative�…

Rationale: Reducing the global burden of sepsis, a recognized global health challenge,
requires comprehensive data on the incidence and mortality on a global scale. Objectives�…

Objective Sepsis is a complex and hard-to-define condition with many different interactions
with other disorders. Presently, there are no estimates of the burden of sepsis and�…

Purpose A population-level description and analysis of sepsis-related mortality in China is
key to the planning and assessment of interventional strategies. Methods Retrospective�…

Sepsis is a disorder characterised by systemic inflammation secondary to infection. Despite
recent progress in the understanding and treatment of sepsis, no data or recommendations�…

OBJECTIVES: Sepsis is a life-threatening condition and is one of the leading causes of
death in the United States. The burden of sepsis-related mortality in the United States in�…

Objectives To quantify mortality associated with sepsis in the whole population of England.
Design Descriptive statistics of multiple cause of death data. Setting England between 2001�…

Sepsis, defined as the condition arising when the host response to infection causes organ
dysfunction in the host, remains a major killer. Probably the most often quoted article on the�…

Objectives: Sepsis generates significant global acute illness burden. The international
variations in sepsis epidemiology (illness burden) have implications for region specific�…