It is well known that stress is a significant risk factor for the development of drug addiction
and addiction relapse. Remarkably, the cognitive processes involved in the effects of stress�…

This review provides a neuroadaptive perspective regarding the role of the hormonal and
brain stress systems in drug addiction with a focus on the changes that occur during the�…

A growing clinical literature indicates that there is a link between substance abuse and
stress. One explanation for the high co-occurrence of stress-related disorders and drug�…

Stress is a well‐known risk factor in the development of addiction and in addiction relapse
vulnerability. A series of population‐based and epidemiological studies have identified�…

This article will review data obtained from both clinical and preclinical investigations
demonstrating that exposure to stress has a significant impact on drug addiction. The�…

Rationale: The notion that stress leads to drug abuse in vulnerable individuals and relapse
in addicts is not new. Most major theories of addiction postulate that stress plays an�…

Relapse is a major characteristic of drug addiction disorders and remains the primary
problem for treatment. Recently, there has been hope that these disorders may be amenable�…

A number of studies have assessed the effects of psychoactive drugs on stress biology, the
neuroadaptations resulting from chronic drug use on stress biology, and their effects on�…

Based on brain imaging findings, we present a model according to which addiction emerges
as an imbalance in the information processing and integration among various brain circuits�…

It has long been believed that stress and drug abuse are related. Studies using animal
models have repeatedly demonstrated that stressed animals more readily self-administer�…