[HTML][HTML] Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atag�nd�z, F Tabak…�- Clinical�…, 2020 - Springer
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as�…

[HTML][HTML] COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire�- Frontiers in immunology, 2020 - frontiersin.org
The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory�…

[HTML][HTML] Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs�…

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan…�- Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious�…

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi…�- Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like�…

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger…�- Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine�…

[HTML][HTML] Cytokine storm and immunomodulatory therapy in COVID-19: role of chloroquine and anti-IL-6 monoclonal antibodies

M Zhao�- International journal of antimicrobial agents, 2020 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus-2, the causative agent of coronavirus
disease 2019 (COVID-19), was declared a pandemic by the World Health Organization on�…

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah…�- Frontiers in�…, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract�…

[HTML][HTML] Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter�…

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh…�- Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though�…

[HTML][HTML] Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen�- Frontiers in immunology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes
coronavirus disease 2019 (COVID-19). As of 25 May 2020, the outbreak of COVID-19 has�…

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta�- Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia�…