Osteoprotegerin (OPG) Expression by Breast Cancer Cells in vitro and Breast Tumours in vivo – A Role in Tumour Cell Survival?

I Holen, SS Cross, HL Neville-Webbe, NA Cross…�- Breast cancer research�…, 2005 - Springer
In addition to its role in bone turnover, osteoprotegerin (OPG) has been reported to bind to
and inhibit Tumour necrosis factor-related apoptosis inducing ligand (TRAIL). TRAIL is�…

[HTML][HTML] Osteoprotegerin in breast cancer: beyond bone remodeling

M Weichhaus, STM Chung, L Connelly�- Molecular cancer, 2015 - Springer
Osteoprotegerin (OPG) is a secreted protein and member of the Tumor Necrosis Factor
(TNF) Receptor superfamily. OPG has been well characterized as a regulator of bone�…

Osteoprotegerin production by breast cancer cells is suppressed by dexamethasone and confers resistance against TRAIL‐induced apoptosis

TD Rachner, P Benad, M Rauner…�- Journal of cellular�…, 2009 - Wiley Online Library
Osteoprotegerin (OPG) is a decoy receptor for receptor activator of NF‐κB ligand (RANKL)
and TNF‐related apoptosis‐inducing ligand (TRAIL). While RANKL is essential for�…

Osteoprotegerin (OPG) produced by bone marrow stromal cells protects breast cancer cells from TRAIL-induced apoptosis

HL Neville-Webbe, NA Cross, CL Eaton…�- Breast cancer research�…, 2004 - Springer
Advanced breast cancer is often associated with metastatic bone disease, causing a number
of serious complications for the patients such as hypercalceamia, pain, nerve compression�…

Expression of osteoprotegerin (OPG), TNF related apoptosis inducing ligand (TRAIL), and receptor activator of nuclear factor κB ligand (RANKL) in human breast�…

C Van Poznak, SS Cross, M Saggese…�- Journal of clinical�…, 2006 - jcp.bmj.com
Background: Osteoprotegerin (OPG) is involved in the regulation of bone turnover through
binding to the receptor activator of nuclear factor κB ligand (RANKL), and has also been�…

Osteoprotegerin expression in triple‐negative breast cancer cells promotes metastasis

M Weichhaus, P Segaran, A Renaud, D Geerts…�- Cancer�…, 2014 - Wiley Online Library
Osteoprotegerin (OPG) is a secreted member of the tumor necrosis factor (TNF) receptor
superfamily that has been well characterized as a negative regulator of bone remodeling�…

[HTML][HTML] Osteoprotegerin rich tumor microenvironment: implications in breast cancer

S Goswami, N Sharma-Walia�- Oncotarget, 2016 - ncbi.nlm.nih.gov
Osteoprotegerin (OPG) is a soluble decoy receptor for tumor necrosis factor (TNF)-related
apoptosis inducing ligand (TRAIL). It belongs to the tumor necrosis factor receptor�…

Osteoprotegrin and the bone homing and colonization potential of breast cancer cells

P Kapoor, LJ Suva, DR Welch…�- Journal of cellular�…, 2008 - Wiley Online Library
Breast cancer cells preferentially metastasize to bone, leading to the formation of primarily
osteolytic lesions. Osteoprotegerin (OPG) plays multifactorial roles in the development of�…

Osteoprotegerin is expressed in colon carcinoma cells

I Pettersen, W Bakkelund, B SMEDSR�D…�- Anticancer�…, 2005 - ar.iiarjournals.org
Background: Osteoprotegerin (OPG), a soluble member of the tumor necrosis factor family, is
produced by various cell types and tissues and plays a key role in the physiological�…

Role of osteoprotegerin (OPG) in cancer

I Holen, CM Shipman�- Clinical science, 2006 - portlandpress.com
OPG (osteoprotegerin), a secreted member of the TNF (tumour necrosis factor) receptor
superfamily, has a variety of biological functions which include the regulation of bone�…