Osteoprotegerin (OPG) Expression by Breast Cancer Cells in vitro and Breast Tumours in vivo – A Role in Tumour Cell Survival?
In addition to its role in bone turnover, osteoprotegerin (OPG) has been reported to bind to
and inhibit Tumour necrosis factor-related apoptosis inducing ligand (TRAIL). TRAIL is�…
and inhibit Tumour necrosis factor-related apoptosis inducing ligand (TRAIL). TRAIL is�…
[HTML][HTML] Osteoprotegerin in breast cancer: beyond bone remodeling
M Weichhaus, STM Chung, L Connelly�- Molecular cancer, 2015 - Springer
Osteoprotegerin (OPG) is a secreted protein and member of the Tumor Necrosis Factor
(TNF) Receptor superfamily. OPG has been well characterized as a regulator of bone�…
(TNF) Receptor superfamily. OPG has been well characterized as a regulator of bone�…
Osteoprotegerin production by breast cancer cells is suppressed by dexamethasone and confers resistance against TRAIL‐induced apoptosis
TD Rachner, P Benad, M Rauner…�- Journal of cellular�…, 2009 - Wiley Online Library
Osteoprotegerin (OPG) is a decoy receptor for receptor activator of NF‐κB ligand (RANKL)
and TNF‐related apoptosis‐inducing ligand (TRAIL). While RANKL is essential for�…
and TNF‐related apoptosis‐inducing ligand (TRAIL). While RANKL is essential for�…
Osteoprotegerin (OPG) produced by bone marrow stromal cells protects breast cancer cells from TRAIL-induced apoptosis
HL Neville-Webbe, NA Cross, CL Eaton…�- Breast cancer research�…, 2004 - Springer
Advanced breast cancer is often associated with metastatic bone disease, causing a number
of serious complications for the patients such as hypercalceamia, pain, nerve compression�…
of serious complications for the patients such as hypercalceamia, pain, nerve compression�…
Expression of osteoprotegerin (OPG), TNF related apoptosis inducing ligand (TRAIL), and receptor activator of nuclear factor κB ligand (RANKL) in human breast�…
C Van Poznak, SS Cross, M Saggese…�- Journal of clinical�…, 2006 - jcp.bmj.com
Background: Osteoprotegerin (OPG) is involved in the regulation of bone turnover through
binding to the receptor activator of nuclear factor κB ligand (RANKL), and has also been�…
binding to the receptor activator of nuclear factor κB ligand (RANKL), and has also been�…
Osteoprotegerin expression in triple‐negative breast cancer cells promotes metastasis
M Weichhaus, P Segaran, A Renaud, D Geerts…�- Cancer�…, 2014 - Wiley Online Library
Osteoprotegerin (OPG) is a secreted member of the tumor necrosis factor (TNF) receptor
superfamily that has been well characterized as a negative regulator of bone remodeling�…
superfamily that has been well characterized as a negative regulator of bone remodeling�…
[HTML][HTML] Osteoprotegerin rich tumor microenvironment: implications in breast cancer
S Goswami, N Sharma-Walia�- Oncotarget, 2016 - ncbi.nlm.nih.gov
Osteoprotegerin (OPG) is a soluble decoy receptor for tumor necrosis factor (TNF)-related
apoptosis inducing ligand (TRAIL). It belongs to the tumor necrosis factor receptor�…
apoptosis inducing ligand (TRAIL). It belongs to the tumor necrosis factor receptor�…
Osteoprotegrin and the bone homing and colonization potential of breast cancer cells
Breast cancer cells preferentially metastasize to bone, leading to the formation of primarily
osteolytic lesions. Osteoprotegerin (OPG) plays multifactorial roles in the development of�…
osteolytic lesions. Osteoprotegerin (OPG) plays multifactorial roles in the development of�…
Osteoprotegerin is expressed in colon carcinoma cells
I Pettersen, W Bakkelund, B SMEDSR�D…�- Anticancer�…, 2005 - ar.iiarjournals.org
Background: Osteoprotegerin (OPG), a soluble member of the tumor necrosis factor family, is
produced by various cell types and tissues and plays a key role in the physiological�…
produced by various cell types and tissues and plays a key role in the physiological�…
Role of osteoprotegerin (OPG) in cancer
I Holen, CM Shipman�- Clinical science, 2006 - portlandpress.com
OPG (osteoprotegerin), a secreted member of the TNF (tumour necrosis factor) receptor
superfamily, has a variety of biological functions which include the regulation of bone�…
superfamily, has a variety of biological functions which include the regulation of bone�…
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