Environmental nutrient levels impact cancer cell metabolism, resulting in context-dependent
gene essentiality,. Here, using loss-of-function screening based on RNA interference, we�…

Ferroptosis is an iron-dependent form of necrotic cell death marked by oxidative damage to
phospholipids,. To date, ferroptosis has been thought to be controlled only by the�…

Ferroptosis, a cell death process driven by cellular metabolism and iron-dependent lipid
peroxidation, has been implicated in diseases such as ischaemic organ damage and�…

Ferroptosis is a form of regulated cell death that is caused by the iron-dependent
peroxidation of lipids,. The glutathione-dependent lipid hydroperoxidase glutathione�…

Ferroptosis is evolving as a highly promising approach to combat difficult-to-treat tumour
entities including therapy-refractory and dedifferentiating cancers,–. Recently, ferroptosis�…

Ferroptosis, a form of non-apoptotic cell death that is hallmarked by lipid peroxidation of
cellular membranes, has gained considerable attention as it is considered a potential�…

Ferroptosis, a form of non-apoptotic cell death that is hallmarked by lipid peroxidation of
cellular membranes, has gained considerable attention as it is considered a potential�…

Dear Editor, Ferroptosis is a form of non-apoptotic cell death characterized by the
accumulation of iron-dependent lipid peroxides and oxidative damage to cell membrane. 1�…

Ferroptosis, marked by iron-dependent lipid peroxidation, may present an Achilles heel for
the treatment of cancers. Ferroptosis suppressor protein-1 (FSP1), as the second ferroptosis�…

The mechanism of action of eprenetapopt (APR-246, PRIMA-1MET) as an anticancer agent
remains unresolved, although the clinical development of eprenetapopt focuses on its�…