In almost all tissues, including the brain, folates are required for one-carbon transfer
reactions, which are essential for the synthesis of DNA and RNA nucleotides, the�…

Folate and brain function in the elderly : Current Opinion in Clinical Nutrition & Metabolic
Care Folate and brain function in the elderly : Current Opinion in Clinical Nutrition &�…

The relevance of low folate levels as determinants of cognitive deficits and the usefulness of
folate supplementation in the treatment of cognitive deficits was reviewed from the literature�…

Background: This study is to examine the effects of folic acid supplementation on cognitive
function in Chinese older adults with mild cognitive impairment who are unexposed to folic�…

Background: Low folate status is associated with poor cognitive function and dementia in the
elderly. Since 1998, grain products in the United States have been fortified with folic acid�…

Background Deficiencies in folate and vitamin B 12 have been associated with
neurodegenerative disease. Objective To examine the association between rates of age�…

Background Low folate and raised homocysteine concentrations in blood are associated
with poor cognitive performance in the general population. As part of the FACIT trial to�…

Adequate levels of folate are crucial for proper brain and body functioning. Folate
deficiencies may lead to an increased risk of depression and poorer antidepressant�…

Elderly persons are especially exposed to folate deficiency, where normal/subnormal folate
levels do not exclude tissue deficiency. Accompanying diseases, medication, and lifestyle�…

Folic acid plays an important role in neuroplasticity and in the maintenance of neuronal
integrity. Folate is a co-factor in one-carbon metabolism during which it promotes the�…